Results 41 to 50 of about 473,299 (218)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Investigation on the Separation Performance of a Multicyclone Separator for Natural Gas Purification
Aerosol and Air Quality Research, 2014 This study evaluated the separation efficiency and developed a pressure drop model for a multicyclone separator used for natural gas purification. The collection and grade efficiencies of a multicyclone separator with 15 single cyclone separators were evaluated at inlet velocities of 6–24 m/s and particle concentrations of 30–2000 mg/m 3 at atmospheric
Zhiyi Xiong, Zhongli Ji, Xiaolin Wu
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Effect of Aerosol Loading on Separation Performance of PM2.5 Cyclone Separators
Aerosol and Air Quality Research, 2018 The adverse health effects of particulate matter less than 2.5 µm in diameter (PM2.5) have drawn increasing attention over the past several decades. To obtain reliable measurements, it is critical to efficiently separate PM2.5 in the airstream from the beginning till the end of sampling.
Chih-Wei Lin +5 more
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Effect of Water Vapor on CO2 Separation Performance of Membrane Separator.
KAGAKU KOGAKU RONBUNSHU, 1999 飽和水蒸気を含むCO2, N2混合ガスからCO2を中空糸膜モジュールを用いて分離する実験を行った.膜モジュールを透過したガス中のCO2/N2モル比は水蒸気を含まない混合ガスからCO2を分離した場合よりも大きかった.モジュール内のガスのプローパターンで比較すると飽和水蒸気を含む混合ガスからのCO2分離は並流の方が向流よりも優れていた.コンピューターシミュレーションによりモジュール内の気体の挙動を解析した結果, 水蒸気の膜透過速度がCO2に比べて大きいため飽和水蒸気を含むことにより膜の透過側のCO2モル分率が小さくなり, CO2の分離推進力が大きくなることが判った.また, 並流ではモジュール内の全領域に水蒸気が存在するのに対し ...
MATSUMIYA, NORIFUMI +3 more
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source