Results 91 to 100 of about 3,495,328 (352)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

On the magnitude, frequency, and nature of marriage dissolution in Italy: insights from vital statistics and life-table analysis

open access: yesGenus, 2021
Legal separation is a crucial step in the dissolving of marriages in Italy. Marriage and legal separation data come from administrative data sources and have been part of the civil registration and vital statistics system for a long time. These data make
Antonella Guarneri   +3 more
doaj   +1 more source

On the sign of kurtosis near the QCD critical point

open access: yes, 2011
We point out that the quartic cumulant (and kurtosis) of the order parameter fluctuations is universally negative when the critical point is approached on the crossover side of the phase separation line.
J. Zinn-Justin   +3 more
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Convict(ed) Women—Then and Now: Lessons of History for Today

open access: yesInternational Journal for Crime, Justice and Social Democracy, 2023
This paper explores the lives of convict women transported to Van Diemen’s Land (Tasmania) in the 1800’s, with the aim to better understand the process of desistance and reintegration for contemporary female offenders.
Jessica Smith, Rob White
doaj   +1 more source

Analytic Models for Separable Statistical Multiplexing [PDF]

open access: yes, 1996
We investigate a multiplexing scheme for ATM that statistically multiplexes VCs of the same service, but does not statistically multiplex across services. The scheme is implemented by allocating bandwidth to each service. In the static version, the allocations are fixed; in the dynamic version, the allocations depend on the numbers of VCs in progress ...
Veronique Veque, Keith W. Ross
openaire   +2 more sources

Gap statistics of two interacting run and tumble particles in one dimension [PDF]

open access: yesJournal of Physics A: Mathematical and Theoretical, 2019
We study the dynamics of the separation (gap) between a pair of interacting run and tumble particles moving in one dimension in the presence of additional thermal noise. On a ring geometry the distribution of the gap approaches a steady state.
Arghya Das, A. Dhar, A. Kundu
semanticscholar   +1 more source

Gravitational Lensing Statistics in Universes Dominated by Dark Energy

open access: yes, 2003
We study lens statistics in flat, low-density universes with different equations of state $w=p_Q/\rho_Q$ for the dark energy component. Dark energy modifies the distance-redshift relation and the mass function of dark matter halos leading to changes in ...
Bartelmann M.   +7 more
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Colour Separation and Aversion

open access: yesi-Perception, 2012
Aversion to achromatic patterns is well documented but relatively little is known about discomfort from chromatic patterns. Large colour differences are uncommon in the natural environment and deviation from natural statistics makes images uncomfortable (
Sarah M Haigh   +5 more
doaj   +1 more source

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