Results 91 to 100 of about 1,164,827 (340)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Cross-Identification Performance from Simulated Detections: GALEX and SDSS

open access: yes, 2009
We investigate the quality of associations of astronomical sources from multi-wavelength observations using simulated detections that are realistic in terms of their astrometric accuracy, small-scale clustering properties and selection functions.
Alexander S. Szalay   +11 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Blind Separation of Nonstationary Sources Based on Spatial Time-Frequency Distributions

open access: yesEURASIP Journal on Advances in Signal Processing, 2006
Blind source separation (BSS) based on spatial time-frequency distributions (STFDs) provides improved performance over blind source separation methods based on second-order statistics, when dealing with signals that are localized in the time-frequency ...
Zhang Yimin, Amin Moeness G
doaj   +1 more source

Separators - a new statistic for permutations

open access: yes, 2019
A digit $ _j$ in a permutation $ =[ _1,\ldots, _n]\in S_n$ is defined to be a separator of $ $ if by omitting it from $ $ we get a new $2-$block. In this work we introduce a new statistic, the number of separators, on the symmetric group $S_n$ and calculate its distribution over $S_n$.
Bagno, Eli   +3 more
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Assessment of Correlation between Psychological Separation from Parents, and the General Health of a Group of Students of University of Tehran and Shahed University, 2011-2012, Iran

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives:The role of psychological separation of means of achieving an independent sense of self with no need to break with parents has been proved in young person or adult compromising specificity in different cultures.
Sousan Salary   +2 more
doaj  

The large-scale correlations of multi-cell densities and profiles, implications for cosmic variance estimates

open access: yes, 2016
In order to quantify the error budget in the measured probability distribution functions of cell densities, the two-point statistics of cosmic densities in concentric spheres is investigated.
Bernardeau, Francis   +2 more
core   +3 more sources

Statistical separability of spectral classes of blighted corn

open access: yesRemote Sensing of Environment, 1974
A study was conducted to determine the statistical separability of multispectral measurements from corn having varying levels of southern corn leaf blight severity. Multispectral scanner data in twelve spectral channels in the wavelength range 0.4 to 11.7 microns were analyzed for ten selected flightlines of the 1971 Corn Blight Watch Experiment.
Kumar, R., Silva, L.
openaire   +3 more sources

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