Results 101 to 110 of about 2,813,997 (315)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Department of Applied Mathematics and Statistics newsletter, September 5, 2023

open access: yes, 2023
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

core  

Blind Voice Separation Based on Empirical Mode Decomposition and Grey Wolf Optimizer Algorithm

open access: yesIranian Journal of Electrical and Electronic Engineering, 2019
Blind voice separation refers to retrieve a set of independent sources combined by an unknown destructive system. The proposed separation procedure is based on processing of the observed sources without having any information about the combinational ...
S. Mavaddati
doaj  

Algorithm for Reducing the Number of Forwarding Rules Created by SDN Applications

open access: yesМоделирование и анализ информационных систем, 2019
Software-Defined Networking (SDN) is a network architecture that introduces a physical separation of data-plane from control-plane. It implements a new way of analyzing network statistics through counters installed on forwarding rules.
Ivan S. Petrov
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Anaesthetic Management of Conjoined Twins′ Separation Surgery

open access: yesIndian Journal of Anaesthesia, 2009
Anaesthesia for conjoined twins, either for separation surgery, or for MRI or other evaluation procedures is an enormous challenge to the paediatric anaesthesiologist.
Kolli S Chalam
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Australian demographic statistics, Sep 2015

open access: yes, 2016
Quarterly estimates of total resident population for states, territories and Australia. About this release Quarterly estimates of total resident population for states, territories and Australia.
Australian Bureau of Statistics
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Maandbulletin van statistiek = Monthly bulletin of statistics /

open access: yes
Description based on: Vol. 35, no. 2/3 (feb./maart 1956).Title varies slightly: vol. 36, no. 1 (Jan 1957)-v. 38, no. 12 (Dec. 1959), English title preceeds title in Afrikaans; v. 39, no. 1 (Jan 1960)-v. 39, no.
South Africa. Bureau of Census and Statistics.
core  

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