Results 91 to 100 of about 2,813,997 (315)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Pocket Statistics 2009

open access: yes, 2009
A compact selection of statistics on the social security programmes administered by the Kela. Including both tables and charts, the Pocket statistics presents key data on the benefits provided by the Kela, supplemented by selected data about programmes ...
Kela
core  

The Epidemiology of Separation Anxiety Disorder in Isfahan Primary School Male Students

open access: yesمجله اپیدمیولوژی ایران, 2012
Background & Objectives: One of the most common anxiety disorders in children is separation anxiety disorder (SAD). The purpose of the present study was to investigate the epidemiology of separation anxiety disorder in Isfahan primary school male student.
A Nassi   +4 more
doaj  

Effective Monoaural Speech Separation through Convolutional Top-Down Multi-View Network

open access: yesFuture Internet
Speech separation, sometimes known as the “cocktail party problem”, is the process of separating individual speech signals from an audio mixture that includes ambient noises and several speakers.
Aye Nyein Aung   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Pocket Statistics 2010

open access: yes, 2010
A compact selection of statistics on the social security programmes administered by the Kela. Including both tables and charts, the Pocket statistics presents key data on the benefits provided by the Kela, supplemented by selected data about programmes ...
Kela
core  

2022-2023 AAAL Statistics

open access: yes
Annual institutional statistics collection for AAAL member libraries.
Statistics, AAAL
core   +1 more source

Department of Applied Mathematics and Statistics newsletter, September 11, 2023

open access: yes, 2023
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

2024-2025 AAAL Statistics

open access: yes
Annual institutional statistics collection for AAAL member ...
Statistics, AAAL
core   +1 more source

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