Results 121 to 130 of about 2,813,997 (315)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Parental separation penalties among university students in Italy
GenusThis paper addresses the long-standing question of whether parental separation shapes offspring school performance drawing on retrospective data from a group of university students in Italy, a country that has historically had very low separation rates ...
Luca Maria Pesando, Manuela Stranges
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Effect of Flotation on High Purification of Different Vein Quartzs
Kuangchan zonghe liyong[Objective] Vein quartz is an important high-purity quartz material. To explore the influence of different technological processes on the content and occurrence form of fluid inclusions in gangue quartz, and to reveal the variation law of quartz ...
Yuhao HE +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Distribution of Statistics on Separable Permutations Restricted by a Flat Pop
Discrete Applied MathematicsFinding distributions of statistics in pattern-avoiding permutations has attracted significant attention in the literature. In particular, Chen, Kitaev, and Zhang derived functional equations for the joint distributions of any subset of classical minima and maxima statistics, as well as for the joint distributions of ascents and descents in separable ...
Gao, Alice L.L. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Department of Applied Mathematics and Statistics newsletter, November 13, 2023
, 2023 Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
core
Separation of Health and Statistics [PDF]
JNCI Journal of the National Cancer Institute, 2008 openaire +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source