Results 121 to 130 of about 1,164,827 (340)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
AIP AdvancesThe separation and turbulent transition of the flow in a compressor blade channel are investigated through direct numerical simulations (DNS) at a Reynolds number of 1.367 × 105.
Yang Liu +3 more
doaj +1 more source
Separation of Dependent Sources in Astrophysical Radiation Maps using Second Order Statistics [PDF]
, 2004 Luigi Bedini +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Dynamical localization of chaotic eigenstates in the mixed-type systems: spectral statistics in a billiard system after separation of regular and chaotic eigenstates [PDF]
, 2013 Benjamin Batistić, Marko Robnik
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Effects of periodic unsteadiness of a rocket engine plume on the plume-induced separation shock wave [PDF]
A wind tunnel investigation was conducted to study the flow field in which separation is caused by an expanding plume, with emphasis on effects associated with periodic unsteadiness in the plume.
Doughty, J. O.
core +1 more source
The statistics of wide-separation lenses
, 2000 The probability that high-redshift sources are gravitationally-lensed with large image separations (i.e., greater than can be produced by galactic deflectors) is determined by the cosmological population of group- and cluster-sized halos. Thus the observed frequency of wide-separation lensed quasars can be used to constrain not only the halo ...
openaire +2 more sources
Degree of phase-space separability of statistical pulses
Optics Express, 2012 We introduce the concept of phase-space separability degree of statistical pulses and show how it can be determined using a bi-orthogonal decomposition of the pulse Wigner distribution. We present explicit analytical results for the case of chirped gaussian Schell-model pulses. We also demonstrate that chirping of the pulsed source serves as a powerful
openaire +2 more sources
A New Method of Blind Source Separation Using Single-Channel ICA Based on Higher-Order Statistics [PDF]
, 2015 Guangkuo Lu +3 more
openalex +1 more source