Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Department of Applied Mathematics and Statistics newsletter, February 19, 2024
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Frequency-Domain Second-Order Decorrelation with Compact Time-Domain Regularization for Convolutive Underwater Acoustic Source Separation. [PDF]
Sensors (Basel)Cao H, Yang T, He Q, Yiu KC.
europepmc +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Cloud-Plots for Spherical Data With Applications to Glaucoma and Gait Cyclograms. [PDF]
Stat MedJammalamadaka SR, Abuzaid AH.
europepmc +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Department of Applied Mathematics and Statistics Newsletter, September 8, 2025
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Symptom epidemiology, demographic correlates, and differentiation between cognitive disengagement syndrome symptoms and ADHD symptoms in a large nonprobability sample of Iranian adolescents and adults. [PDF]
BMC PsychiatryAbdolmohamadi K +3 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Loneliness as a mediator between family separation and life satisfaction among Ukrainian refugee women in Germany. [PDF]
Sci RepLevchuk N +3 more
europepmc +1 more source