Results 71 to 80 of about 1,164,827 (340)

Gravitational lensing statistical properties in general FRW cosmologies with dark energy component(s): analytic results [PDF]

open access: yes, 2000
Various astronomical observations have been consistently making a strong case for the existence of a component of dark energy with negative pressure in the universe.
Briel U. G.   +7 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Exploiting Acoustic Similarity of Propagating Paths for Audio Signal Separation

open access: yesEURASIP Journal on Advances in Signal Processing, 2003
Blind signal separation can easily find its position in audio applications where mutually independent sources need to be separated from their microphone mixtures while both room acoustics and sources are unknown.
Yin Bin, Sommen Piet CW, He Peiyu
doaj   +1 more source

Model Order Selection for Collision Multiplicity Estimation [PDF]

open access: yes, 2012
The collision multiplicity (CM) is the number of users involved in a collision. The CM estimation is an essential step in multi-packet reception (MPR) techniques and in collision resolution (CR) methods.
Escrig, Benoît
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Psychometric evaluation of the Decision Support System (DSS) for municipal nurses encountering health deterioration among older adults

open access: yesBMC Geriatrics
Background A valid and reliable tool is crucial for municipal registered nurses (RNs) to make quick decisions in older adults who show rapid signs of health deterioration.
Annica Kihlgren   +5 more
doaj   +1 more source

On the sign of kurtosis near the QCD critical point

open access: yes, 2011
We point out that the quartic cumulant (and kurtosis) of the order parameter fluctuations is universally negative when the critical point is approached on the crossover side of the phase separation line.
J. Zinn-Justin   +3 more
core   +1 more source

Two New Gravitationally Lensed Double Quasars from the Sloan Digital Sky Survey [PDF]

open access: yes, 2005
We report the discoveries of the two-image gravitationally lensed quasars, SDSS J0746+4403 and SDSS J1406+6126, selected from the Sloan Digital Sky Survey (SDSS).
Bade N.   +15 more
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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