Results 31 to 40 of about 39,291 (307)

Some Results on Ethnic Conflicts Based on Evolutionary Game Simulation

open access: yes, 2013
The force of the ethnic separatism, essentially origining from negative effect of ethnic identity, is damaging the stability and harmony of multiethnic countries.
Liu, Yuhang   +5 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Czynniki destabilizacji politycznej w Karaczajo-Czerkiesji: separatyzm etniczny i fundamentalizm religijny [PDF]

open access: yes, 2018
The Republic of Karachay-Cherkessia is among the most unstable entities of the Russian federation. Whereas the ideas of radical political Islam enjoy little popularity there, the ethnic structure is exceptionally complex, which is not reflected in the ...
Sieradzan, Przemysław J.
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A new age of global security: The 'Ukrainian question' and 'Kosovo precedent' [PDF]

open access: yesВојно дело, 2017
The research topic of this article is the 'Ukrainian Question' in perspective of 'Kosovo precedent' within the framework of international law, current stream of international relations, contemporary world politics and global security.
Sotirović Vladislav B.
doaj   +1 more source

Race Separatism in the Family: More on the Transracial Adoption Debate [PDF]

open access: yes, 1995
Some twenty-five years ago a trial court in Virginia upheld the state ban on interracial marriage, reasoning that God created different races and, accordingly, that it was natural to maintain racial purity, and unnatural to engage in racial mixing.
Bartholet, Elizabeth
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Ethnic Separatism in Pakistan as a Threat to Regional Security

open access: yesVestnik RUDN. International Relations, 2015
At present ethnic separatism is shown in various regions practically on all continents and it is the same serious call of the international stability and safety, as religious extremism and drugs.
Adam Isaevich Khahkhanov
doaj  

South Tyrol Issue as a Factor of Interstate Relations between Italy and Austria

open access: yesУправленческое консультирование, 2020
The research highlights the ethnopolitical conflict within the European Union (using the example of the South Tyrol autonomy). The article states the reasons for the formation of separatist sentiments on the territory of this region, considers in detail ...
M. M. Shumilov, O. I. Shmidt
doaj   +1 more source

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