Results 41 to 50 of about 4,449 (296)
A new age of global security: The 'Ukrainian question' and 'Kosovo precedent' [PDF]
Војно дело, 2017 The research topic of this article is the 'Ukrainian Question' in perspective of 'Kosovo precedent' within the framework of international law, current stream of international relations, contemporary world politics and global security.
Sotirović Vladislav B.
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
South Tyrol Issue as a Factor of Interstate Relations between Italy and Austria
Управленческое консультирование, 2020 The research highlights the ethnopolitical conflict within the European Union (using the example of the South Tyrol autonomy). The article states the reasons for the formation of separatist sentiments on the territory of this region, considers in detail ...
M. M. Shumilov, O. I. Shmidt
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Support for Separatism in Ethnic Republics of the Russian Federation [PDF]
, 2008 This study examines popular support for separatism among Russians and non-Russian titular nationalities (titulars) in 10 ethnic republics of the Russian Federation: Karelia, Komi, Tatarstan, Bashkortostan, Udmurtia, Adygea, Dagestan, Kabardino-Balkaria ...
Hagendoorn, Louk +5 more
core +1 more source