Results 111 to 120 of about 163,198 (278)

Emestrin‐Type Epidithiodiketopiperazines Inhibited Gasdermin D‐Mediated Pyroptosis via Caspase‐3/7 Activation

open access: yesMedComm, Volume 7, Issue 1, January 2026.
This study demonstrates that emestrin‐type ETPs suppress GSDMD‐mediated pyroptosis through caspase‐3/7 activation, thereby attenuating inflammatory responses and conferring protection against sepsis. In THP‐1 macrophages, ETPs significantly reduced pyroptosis and secretion of the proinflammatory cytokines IL‐1β and IL‐18.
Bingchuan Geng   +16 more
wiley   +1 more source

Transferrin-polycation conjugates as carriers for DNA uptake into cells. [PDF]

open access: yes, 1990
We have developed a high-efficiency nucleic acid delivery system that uses receptor-mediated endocytosis to carry DNA macromolecules into cells. We accomplished this by conjugating the iron-transport protein transferrin to polycations that bind nucleic ...
Beug, Hartmut   +4 more
core   +1 more source

Preparation of Nanoliposomes Incorporated Leishmania donovani Antigens

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2016
This study was designed to incorporate leishmania donovani antigens in nanoliposomes prepared by size exclusion (using Sephadex G25) and organic solvent (using Chloroform).
Ali A. Taha   +2 more
doaj   +1 more source

Investigating the mechanism of aluminum resistance conferred by aluminum resistance protein 1

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract Aluminum does not play any role in essential biological processes, but in acidic conditions it becomes biologically reactive and highly toxic even at low concentrations. Eukaryotes have developed numerous strategies for detoxification, one of which relies on membrane proteins.
Pavlo Stehantsev   +7 more
wiley   +1 more source

A study of the enzymatic hydrolysis of fish frames using model systems [PDF]

open access: yes, 2011
A model system was employed to study the operating conditions and primary parameters of enzymic hydrolysis of cod proteins. Pancreatin, papain, and bromelain were used to hydrolyse minced cod fillets under controlled conditions and with the rate of ...
Himonides, Aristotelis T.   +2 more
core   +1 more source

Un método sencillo para la medición de la triyodotironina en suero por radioinmunoanálisis utilizando columnas de Sephadex G-25

open access: yesRevista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018
Fragmento Un nuevo método para la medición de la triyodotironina (T3) en suero ha aparecido recientemente en el comercio; puede efectuarse en un corto período de tiempo, aproximadamente 4 horas, en cualquier laboratorio equipado con un contador de ...
Guillermo Arango R., Heinz W. Wahner
doaj   +1 more source

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee   +14 more
wiley   +1 more source

Eotaxin Expression in Sephadex-Induced Lung Injury in Rats [PDF]

open access: bronze, 1999
Ren-Feng Guo   +5 more
openalex   +1 more source

Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials

open access: yesSmall, Volume 22, Issue 5, 22 January 2026.
Nucleic acid‐ligand conjugates combine the distinct properties of macromolecular ligands with the versatility of DNA/RNA nanotechnology. In biomaterial and nanomedicine applications, highly purified products are paramount, requiring reliable synthesis and purification methods.
Nico Alleva   +4 more
wiley   +1 more source

Upconverting Nanoparticle‐Loaded Microneedles for Near‐Infrared Responsive Delivery of Gonadotropins to Increase Success of In Vitro Fertilization

open access: yesSmall, Volume 22, Issue 1, 2 January 2026.
This paper describes the development of an upconverting particle‐integrated microneedle patch that can release the hormone leuprolide when the patch is exposed to near‐infrared light. This system represents proof‐of‐concept of a painless and automated method of delivering drugs at specific times when repeated time‐sensitive injections are required ...
Vivienne Tam   +8 more
wiley   +1 more source

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