Preparative Isolation of Two Prenylated Biflavonoids from the Roots and Rhizomes of Sinopodophyllum emodi by Sephadex LH-20 Column and High-Speed Counter-Current Chromatography [PDF]
Molecules, 2015 Two prenylated biflavonoids, podoverines B–C, were isolated from the dried roots and rhizomes of Sinopodophyllum emodi using a Sephadex LH-20 column (SLHC) and high-speed counter-current chromatography (HSCCC).
Yan-Jun Sun +7 more
doaj +4 more sources
Chemical Constituents of the Deep-Sea-Derived Fungus Talaromyces wortmannii and Their Ferroptosis Inhibitory Activity. [PDF]
Chem BiodiversOne new tyramine derivative (1) and 28 known compounds (2–29) were isolated from deep‐sea‐derived fungus Talaromyces wortmannii. Their structures were elucidated by NMR/MS and computational calculations. Compounds 2 and 6 potently inhibited ferroptosis with EC5₀ values of 4.52 and 13.73 µM.
Ma KX +5 more
europepmc +2 more sources
Constituents From the Flowers of Viburnum macrocephalum f. macrocephalum and Their α-Amylase and α-Glucosidase Inhibitory Activities. [PDF]
Chem BiodiversTwo new cadinane‑type sesquiterpenes, viburetones A and B, were isolated from Viburnum macrocephalum flowers, marking the first cadinane skeletons in this genus. Viburetone A showed dual α‑amylase and α‑glucosidase inhibition comparable to acarbose, and docking clarified its binding.
Chen YJ +5 more
europepmc +2 more sources
Flavasperfurans A and B, Two New Asperfuran Derivatives From the Marine-Derived Fungus Aspergillus flavus. [PDF]
Chem BiodiversTwo new asperfurans (1 and 2) and 23 known compounds from marine Aspergillus flavus were characterized by NMR, HRESIMS, DP4+, and ECD. Asperfuran (3) potently inhibited RSL3‐induced ferroptosis (EC50 = 0.81 µM). ABSTRACT Marine microorganisms represent a prolific reservoir of chemically diverse natural products endowed with considerable therapeutic ...
Wang CX, Zou ZB, Li LS, Gao CH, Yang XW.
europepmc +2 more sources
Extraction and Isolation of Bioactive Compounds From Malpighia glabra L. Leaves: In Vivo Investigation of the Leaf Extract Against Oxidative Stress and Inflammation Triggered by γ-Radiation. [PDF]
Chem BiodiversMalpighia glabra L. leaves extract, enriched with flavonoids and β‐isoarborinol, exhibits antioxidant and anti‐inflammatory activities that moderate γ‐radiation‐induced systemic and tissue harm. The extract preserves intestinal, hepatic, renal, splenic, and systemic integrity by reducing oxidative stress and inflammation, supporting its potential as a ...
Fekry AM +4 more
europepmc +2 more sources
Two New Polyketides From Streptomyces sp. SA61: Isolation, Structure Elucidation, and Insecticidal Activity Against Bemisia tabaci. [PDF]
Chem BiodiversIsolation of six polyketides (including two new compounds, strekingmycins I and J) from earthworm gut‐derived Streptomyces sp. SA61 and their insecticidal activity against third‐instar nymphs of Bemisia tabaci. Strekingmycin A (1) exhibited the most potent activity (LC50 = 5.58 µg/mL), comparable to the commercial insecticide spirotetramat. ABSTRACT To
Cui P, Chen J, Zhu Z, Liu F, Yu Z.
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Food Chemistry: X, 2023 The function of proanthocyanidins (PAs) relies on their structure and requires high-purity PAs. Though Sephadex LH-20 gel permeation chromatography (GPC) is expected to separate PAs based on structure, its usage rules and mechanisms remain unclear.
Xiaoyi Chen +4 more
doaj +1 more source
Current Research in Food Science, 2023 In this study, flavonoids were extracted from pomelo peels and naringin was isolated from the flavonoid extract. The effects of extraction parameters, namely, ethanol concentration, solid-to-liquid ratio, and extraction time, on the yield of flavonoids ...
Yuchen Shangguan +7 more
doaj +1 more source
OENO One, 2022 The effect of wine age on tannin chemistry and tannin activity values was investigated in red wine extracts according to a chemosensory approach. Sixteen Pinotage red wines of multiple vintages (2003-2018) were each isolated into four distinct polymeric ...
Brannigan du Preez +3 more
doaj +1 more source
The Iraqi Journal of Medical SciencesBackground: Siderophores are crucial for the proliferation of many disease-causing bacteria and also have significant functions in the transportation of non-iron metals, defense against oxidative stress, antibiotic effectiveness, interactions ...
Reyam Jaber +2 more
doaj +9 more sources