Results 141 to 150 of about 673,315 (318)

Penicillin in the Treatment of Neonatal Sepsis [PDF]

open access: bronze, 1946
F. M. B. Allen   +2 more
openalex   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang   +4 more
wiley   +1 more source

SepAl: Sepsis Alerts On Low Power Wearables With Digital Biomarkers and On-Device Tiny Machine Learning [PDF]

open access: yes
Sepsis is a lethal syndrome of organ dysfunction that is triggered by an infection and claims 11 million lives per year globally. Prognostic algorithms based on deep learning have shown promise in detecting the onset of sepsis hours before the actual event but use a large number of bio-markers, including vital signs and laboratory tests.
arxiv   +1 more source

Comparison of Clinical Scores for Predicting Stroke‐Associated Pneumonia After Acute Ischemic Stroke

open access: yesAGING MEDICINE, EarlyView.
Our study compared the discrimination and calibration of the Kwon Pneumonia Score, A2DS2 score, PANTHERIS score, AIS‐APS score, ISAN score, and PASS score in SAP identification; of these, the AIS‐APS score showed the best performance. ABSTRACT Objectives To compare the discrimination and calibration of six risk scoring systems in the assessment of ...
Linlin Wang   +8 more
wiley   +1 more source

A rat model of multicompartmental traumatic injury and hemorrhagic shock induces bone marrow dysfunction and profound anemia

open access: yesAnimal Models and Experimental Medicine
Background Severe trauma is associated with systemic inflammation and organ dysfunction. Preclinical rodent trauma models are the mainstay of postinjury research but have been criticized for not fully replicating severe human trauma.
Lauren S. Kelly   +7 more
doaj   +1 more source

Bayesian Learning of Clinically Meaningful Sepsis Phenotypes in Northern Tanzania [PDF]

open access: yesarXiv
Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Recently, researchers have hypothesized that sepsis consists of a heterogeneous spectrum of distinct subtypes, motivating several studies to identify clusters of sepsis patients that correspond to subtypes, with the long-term goal of using these clusters to ...
arxiv  

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

open access: yesIntensive Care Medicine, 2017
A. Rhodes   +64 more
semanticscholar   +1 more source

ICU-Sepsis: A Benchmark MDP Built from Real Medical Data [PDF]

open access: yesarXiv
We present ICU-Sepsis, an environment that can be used in benchmarks for evaluating reinforcement learning (RL) algorithms. Sepsis management is a complex task that has been an important topic in applied RL research in recent years. Therefore, MDPs that model sepsis management can serve as part of a benchmark to evaluate RL algorithms on a challenging ...
arxiv  

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