Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
Impact of hypertrophic pattern and obstruction on cardiovascular magnetic resonance myocardial strain and left atrioventricular coupling in hypertrophic cardiomyopathy: a retrospective study. [PDF]
Li Y, Li Z, Chen S, Long L.
europepmc +1 more source
ABSTRACT Background and Aim Epithelial‐myoepithelial carcinoma (EMC), a malignant tumor with biphasic epithelial and myoepithelial differentiation, is typically a salivary gland neoplasm. Contrastingly, myoepithelial carcinoma (MEC) predominantly comprises myoepithelial cells.
Ryo Nagao +13 more
wiley +1 more source
TTN mutation-positive hypertrophic cardiomyopathy in congenitally corrected transposition of the great arteries: A rare coexistence. [PDF]
Chakraborty S +3 more
europepmc +1 more source
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura +10 more
wiley +1 more source
Asymmetric wall-stress heterogeneity defines a stretch-activated arrhythmogenic substrate beyond ejection fraction in dilated cardiomyopathy: an in silico study. [PDF]
Amit A.
europepmc +1 more source
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto +14 more
wiley +1 more source
Unusual hypertrophic cardiomyopathy with severe right ventricular outflow tract obstruction and two septal aneurysms: a case report. [PDF]
Sun Y, Liu S, Li J.
europepmc +1 more source
ABSTRACT Introduction Patients with repaired tetralogy of Fallot (rTOF) remain at risk of ventricular tachycardia (VT). This risk is most commonly related to slow conduction within the septal isthmus, which is defined as the region between the ventricular septal defect (VSD) patch and adjacent valvular annuli.
Yuki Matsuoka +8 more
wiley +1 more source
Sudden cardiac death in a child with low-risk hypertrophic cardiomyopathy: limitations of current pediatric risk stratification-a case report. [PDF]
Bensalah S +4 more
europepmc +1 more source

