Results 51 to 60 of about 107,014 (181)
Background: The outcomes after septal myectomy in young children and infants with hypertrophic obstructive cardiomyopathy (HOCM) are not clear. The study sought to report the outcomes after septal myectomy in young children and infants and identify the ...
Shuo Dong +9 more
semanticscholar +1 more source
Abstract Background and Purpose Mavacamten (MAVA) is a novel small molecule inhibitor of cardiac myosin, mitigating cardiomyocyte hypercontractility in patients with hypertrophic obstructive cardiomyopathy (HOCM). Despite its recent approval for clinical use, the transcriptional and functional impacts of MAVA remain not well understood.
Elisa Kiselev +36 more
wiley +1 more source
Contemporary Surgical Treatment for Hypertrophic Cardiomyopathy [PDF]
Hypertrophic cardiomyopathy is the most common cause of sudden death in young athletes. Surgical septal myectomy is highly effective for the patients with hypertrophic obstructive cardiomyopathy, which is refractory to medical treatment.
Murashita, Takashi
core +1 more source
Background Coronary microvascular dysfunction (CMD) is a pathophysiological mechanism underlying hypertrophic obstructive cardiomyopathy (HOCM). However, few studies have investigated the potential effect of transapical beating-heart septal myectomy (TA ...
Yun Zhao +9 more
semanticscholar +1 more source
Cardiovascular Health in Women—Across the Lifespan
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar +5 more
wiley +1 more source
3D printing is a transformative technology in congenital heart disease [PDF]
Survival in congenital heart disease has steadily improved since 1938, when Dr. Robert Gross successfully ligated for the first time a patent ductus arteriosus in a 7-year-old child.
Anwar +117 more
core +3 more sources
Postoperative Fluoroscopic Appearance After Flexible Endoscopic Zenker's Diverticulotomy
We perform a retrospective study on patients undergoing flexible Zenker's diverticulotomy surgery and report changes in the objective fluoroscopic appearance as well as patient‐reported outcome measures. ABSTRACT Objective Flexible approach to treating Zenker's diverticulum (ZD) has gained traction in recent years. However, objective measures comparing
Shumon I. Dhar +7 more
wiley +1 more source
Effects of septal myectomy on left atrial and left ventricular function in obstructive hypertrophic cardiomyopathy [PDF]
Kyung Eun Ha +8 more
openalex +1 more source
Impact of sex on timing and clinical outcome of septal myectomy for obstructive hypertrophic cardiomyopathy [PDF]
Background: Sex disparities are common in hypertrophic cardiomyopathy (HCM). Previous research has shown that at time of myectomy, women are older, have greater impairment of diastolic function and more advanced cardiac remodeling. The clinical impact of
Hirsch, A. (Alexander) +5 more
core +1 more source
Does Left Atrial Size and E/e′ Predict Outcomes in Hypertrophic Cardiomyopathy?
The current study followed 233 patients with hypertrophic cardiomyopathy, over a median follow‐up of 8 years. Left atrial size but not E/e' were predictive of outcomes related to atrial arrhythmia, and none were predictive of all‐cause mortality in multivariate analysis.
Brandon Tillson +2 more
wiley +1 more source

