Results 71 to 80 of about 42,011 (217)
PathogensBackground: This study aimed to determine the incidence of septic arthritis across adult age groups in Västra Götaland Region (VGR) of Sweden, while also comparing disease characteristics among different age groups with hematogenous septic arthritis ...
Hanna Alexandersson +2 more
doaj +1 more source
Advanced Science, EarlyView.A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang +12 more
wiley +1 more source
The 9th International RASopathies Symposium
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
Childhood pyogenic septic arthritis as seen in a teaching hospital South East Nigeria
Nigerian Journal of Surgery, 2017 Background: Childhood pyogenic septic arthritis and its associated musculoskeletal morbidity is an important health concern in developing countries.
Njoku Isaac Omoke, Akputa Aja Obasi
doaj +1 more source
Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley +1 more source
Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Transcutaneous electrical nerve stimulation (TENS) improved knee osteoarthritis (KOA) in rats by regulating interleukin‐1β (IL‐1β), IL‐6, and IL‐8 expressions and the bone morphogenetic protein 2 (BMP‐2)/transforming growth factor β (TGF‐β) signaling pathway.
Yan Sun +6 more
wiley +1 more source
Annals of Internal Medicine: Clinical CasesPolyarticular septic arthritis is a condition with significant morbidity and mortality that is rarely seen in immunocompetent adults. We report a case of a 73-year-old man presenting with a 2-day history of polyarthralgia involving bilateral shoulders ...
Kayley Xu +2 more
doaj +1 more source
Annals of Neurology, EarlyView.Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello +20 more
wiley +1 more source
Arthroscopy, EarlyView.Purpose To compare perioperative complications and revision surgery rates between following primary rotator cuff repair among patients with nontobacco nicotine dependence (NTND), no nicotine dependence, and traditional tobacco‐related nicotine dependence.
Samuel A. Florentino +6 more
wiley +1 more source