Results 171 to 180 of about 417,458 (308)

Retropubic versus transobturator slings: Medium‐term satisfaction and overactive bladder outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study compares medium‐term outcomes of retropubic tension‐free vaginal tape (TVT) and transobturator tape (TOT) for stress urinary incontinence (SUI), focusing on patient satisfaction and overactive bladder (OAB) symptoms. Methods This prospective, single‐surgeon cohort study included women with SUI who underwent TVT or TOT at a
Erika Gandelsman   +5 more
wiley   +1 more source

Urethral injury during vaginal delivery: Incidence, management and long‐term outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines the incidence, obstetric risk factors, surgical management, and long‐term outcomes of obstetric‐associated urethral injuries during vaginal deliveries. Methods A retrospective case series was conducted at a single, tertiary university‐affiliated medical center between January 2018 and December 2023.
Yoav Baruch   +5 more
wiley   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

open access: yesiNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen   +6 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos   +10 more
wiley   +1 more source

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