Results 1 to 10 of about 3,156,888 (269)

Genetic Polymorphism and Association of KAP16.6 Gene with Pashmina Fiber Traits in Changthangi Goats

Journal of Natural Fibers, 2022
Pashmina is the fine undercoat of the Changthangi goats (Capra hircus) with Keratin-associated proteins (KAPs) as one of its main structural components. KAPs form a semi-rigid matrix in which the Keratin intermediate filaments (KIFs) are embedded. In the
Syed Shanaz, Tasleem Ahmad Shamas Ganai, Sheikh Firdous Ahmad, Ishraq Hussain, Azmat Aalam Khan, Nazir Ahmad Ganai   +5 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Analysis of Finite Solution Spaces of Second-Order ODE with Dirac Delta Periodic Forcing

Axioms, 2023
Second-order Ordinary Differential Equations (ODEs) with discontinuous forcing have numerous applications in engineering and computational sciences.
Susmit Bagchi
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Molecular Characterization of the 2020 Outbreak of Lumpy Skin Disease in Nepal

Microorganisms, 2022
Lumpy skin disease (LSD) is a transboundary viral disease of cattle and buffaloes transmitted by blood-feeding vectors and causes high morbidity and low-to-moderate mortality.
Pragya Koirala, Irene Kasindi Meki, Manju Maharjan, Bharani Kumar Settypalli, Salina Manandhar, Sanjay Kumar Yadav, Giovanni Cattoli, Charles Euloge Lamien   +7 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

High-quality metagenome assembly from nanopore reads with nanoMDBG

Nature Communications
Third-generation long-read sequencing technologies, significantly improve metagenome assemblies. Highly accurate PacBio HiFi reads can yield hundreds of near-complete metagenome-assembled genomes (MAGs) from a single sample. Recently, the accuracy of the
Gaëtan Benoit, Robert James, Sébastien Raguideau, Georgina Alabone, Tim Goodall, Rayan Chikhi, Christopher Quince   +6 more
doaj   +1 more source

Diagnostic accuracy of Xpert MTB/RIF and Xpert ultra tests in pulmonary and extrapulmonary tuberculosis compared to Löwenstein-Jensen culture

Clinical Epidemiology and Global Health
Background: Tuberculosis (TB) is one of the leading causes of death worldwide. However, an accurate diagnosis contributes to timely treatment, reducing its adverse consequences.
Miguel Hueda-Zavaleta, Juan Gomez-de-la-Torre, Claudia Barletta-Carrillo, Cinthya Flores-Flores, Nilver Piscoche-Botello, Cecilia Miranda-Visalot, Ada Mendoza-Farro, Sujey Gomez-Colque, Álvaro Taype-Rondán, Cesar Copaja-Corzo   +9 more
doaj   +1 more source

Prediction of DNA-Binding Protein–Drug-Binding Sites Using Residue Interaction Networks and Sequence Feature

Frontiers in Bioengineering and Biotechnology, 2022
Identification of protein–ligand binding sites plays a critical role in drug discovery. However, there is still a lack of targeted drug prediction for DNA-binding proteins. This study aims at the binding sites of DNA-binding proteins and drugs, by mining
Wei Wang, Wei Wang, Yu Zhang, Dong Liu, Dong Liu, HongJun Zhang, XianFang Wang, Yun Zhou   +7 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source