Results 111 to 120 of about 4,228,228 (319)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
BIOINFORMATICS APPLICATIONS NOTE doi:10.1093/bioinformatics/btl007 Sequence analysis
Motivation: The first version of the graphical multiple sequence alignment environment QAlign was published in 2003. Heavy response from the molecular-biological user community clearly demonstrated the need for such a platform.
Jens Stoye +4 more
core
Multilocus sequence typing breathes life into a microbial metagenome [PDF]
Shot-gun sequencing of DNA isolated from the environment and the assembly of metagenomes from the resulting data has considerably advanced the study of microbial diversity.
Vandamme Peter +23 more
core +1 more source
Sequence‐to‐sequence alignment using a pendulum
Analysing two or more video sequences of dynamic scenes typically requires time synchronisation between sequences, where this alignment is not always possible using hardware. A particular method will most likely process the entire, frequently lengthy, imaged material, requiring additional processing which normally serves for synchronisation only ...
Tomislav Pribanic +2 more
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Norms of certain operators on weighted L-spaces and Lorentz sequence spaces. [PDF]
The problem addressed is the exact determination of the norms of the classical Hilbert, Copson and averaging operators on weighted spaces and the corresponding Lorentz sequence spaces , with the power weighting sequence or the variant defined by .
Jameson, Graham J. O., Lashkaripour, R.
core
Molecular Epidemiology of Infectious Bursal Disease Virus in Mizoram during 2021–2022
The study was conducted during the tenure period January, 2021–March, 2022 from different regions of Mizoram where outbreaks suspected to be IBDV were screened by agar gel precipitation test (AGPT) for molecular characterization of circulating ...
R. M. Naveen +4 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Data Mining for Simple Sequence Repeats in Oil Palm Expressed Sequence Tags
Expressed Sequence Tags or ESTs are small pieces of DNA sequence that are generated by sequencing either one or both ends of an expressed gene. ESTs provide researchers with a quick and inexpensive route for discovering new genes, for obtaining data on ...
Vadivel Arunachalam, Aikkal Riju
core
Yeni Nesil Dizileme (YND) Hakkında Bilinenler (Literatür Taraması)
Yeni Nesil Dizileme (YND) yönteminin temeli DNA’nın enzimatik reaksiyonlarla kesilerek çok sayıda DNA parçasıyla bir kütüphane oluşturulması ve kütüphaneyi oluşturan DNA parçalarının çoğaltılmasına dayanmaktadır. OMIM istatistiklerine göre günümüzde 6000’
Mustafa DOĞAN +3 more
doaj

