Results 81 to 90 of about 4,228,228 (319)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
We analyze the structure of the state space of chess by means of transition path sampling Monte Carlo simulation. Based on the typical number of moves required to transpose a given configuration of chess pieces into another, we conclude that the state space consists of several pockets between which transitions are rare.
atashpendar, Arshia +2 more
openaire +3 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A report of the seventh annual meeting on Systems Biology: Global Regulation of Gene Expression, 23-27 March 2010, Cold Spring Harbor, USA.
Kellis, Manolis, Rinn, John L.
openaire +5 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Another Set of Sequences, Sub-Sequences, and Sequences of Sequences
In this paper 101 new integer sequences, sub-sequences, and sequences of sequences, together with related unsolved problems and conjectures, are presented. Also, definitions, examples, solved or open questions, and references for each sequence are given.
openaire +2 more sources
This study was carried out to investigate the phenotype and genotype of E. faecalis isolated from the root canal and saliva of primary endodontic patients with periapical lesions.
Zaki Mubarak +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
$A$-sequences, $Z$-sequence, and $B$-sequences of Riordan Matrices
We defined two type $B$-sequences of Riordan arrays and present the $A$-sequence characterization and $Z$-sequence characterization of the Riordan matrices with two type $B$-sequences. The subgroups characterized by $A$-sequences and $Z$-sequences are studied.
openaire +3 more sources
Beatty sequences and Langford sequences
A disjoint covering system (DCS) of Beatty sequences is the collection of Beatty sequences \((\alpha_ i,\beta_ i)=\{\lfloor n_ i+ n_ i\rfloor: n\in{\mathbb{Z}}^ +\}\) with \(\alpha_ i>0\), \(\beta_ i\) real numbers, which partition \(\mathbb{Z}^ +\).
Roger B. Eggleton +2 more
openaire +2 more sources

