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Computer support of DNA sequence analysis
Computer Programs in Biomedicine, 1981The paper describes a package of APL-programs suited for the management and the analysis of DNA sequence data. Most of the application programs are related to experimental work in a DNA sequencing laboratory: Search for overlapping DNA fragments to construct complete DNA sequences; search for restriction sites; computing fragment patterns when cutting ...
R Sommer +3 more
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2009
In this chapter we introduce some of the elementary concepts for analyzing DNA sequences in terms of “words” of length 1 (bases), 2 (base pairs), 3 (triplets, such as codons), restriction sites, etc. The analysis uses some of the basic probability concepts that we have worked with in the previous chapter.
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In this chapter we introduce some of the elementary concepts for analyzing DNA sequences in terms of “words” of length 1 (bases), 2 (base pairs), 3 (triplets, such as codons), restriction sites, etc. The analysis uses some of the basic probability concepts that we have worked with in the previous chapter.
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Computer analysis of DNA and protein sequences
European Journal of Biochemistry, 1991Some recent trends in the development of theoretical methods for DNA and protein sequence analysis are reviewed, with particular emphasis on the design of new databases, motif searches, sequence alignment algorithms and applications of neural networks.
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Recent Advances in DNA Sequence Analysi
CRC Critical Reviews in Biochemistry, 1975(1975). Recent Advances in DNA Sequence Analysi. CRC Critical Reviews in Biochemistry: Vol. 2, No. 4, pp. 455-512.
Ray Wu +3 more
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Video analysis of DNA sequence homologs
Analytical Chemistry, 1992A method for the rapid quantitative analysis of dot blot assays is presented. A video camera, an NTSC compatible frame grabber board, and an AT personal computer are used to read photographic exposures of the assay plate. Image processing and image analysis techniques are used to calculate the orientation of the dot raster and then to compensate for ...
Michael. Ludwig, Robert J. Hartzman
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The Preferential Mode Analysis of DNA Sequence
Journal of Theoretical Biology, 1997After reviewing approaches to the nucleotide correlation of DNA sequences the preferential mode analysis method is emphasized and discussed in detail. The preferred modes and poor modes in coding regions, as well as in introns, 5'-caps and 3'-tails are found through the statistical analysis of sequence data of all kinds of species in GenBank.
Liaofu Luo, Fengmin Ji, Fengmin Ji
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The Analysis of One DNA Sequence
2001Before any analysis of a DNA sequence can take place it is first necessary to determine the actual sequence itself, at least as accurately as is reasonably possible. Unfortunately, technical considerations make it impossible to sequence very long pieces of DNA all at once.
Gregory R. Grant, Warren J. Ewens
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Analysis of rat repetitive DNA sequences
Biochemistry, 1978Parameters of repetitive sequence organization have been measured in the rat genome. Experiments using melting, hydroxylapatite binding, and single strand specific nuclease digestion have been used to measure the number, length, and arrangement of repeated DNA sequences.
Jung-Rung Wu +2 more
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Analysis of Variation in Chloroplast DNA Sequences
2013This chapter introduces and reviews methods for analyzing variation in chloroplast DNA, mainly by polymerase chain reaction (PCR) and subsequent revelation of polymorphisms. Sources for chloroplast primers are discussed, as well as methods such as Sanger sequencing, PCR followed by restriction fragment length polymorphism (RFLP), gel electrophoresis ...
Agnieszka Koziel-Monte +2 more
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Prediction of Function in DNA Sequence Analysis
Journal of Computational Biology, 1995Recognition of function of newly sequenced DNA fragments is an important area of computational molecular biology. Here we present an extensive review of methods for prediction of functional sites, tRNA, and protein-coding genes and discuss possible further directions of research in this area.
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