Results 221 to 230 of about 1,953,840 (266)

The chemistry of protein sequence analysis

2000
N-terminal sequence analysis by Edman chemistry continues to play an important role in the structural analysis of proteins and peptides. Improvements in the sensitivity of the method have been achieved mainly at the level of increasing the sensitivity of the on-line analysis of PTH amino acids by RP-HPLC (reverse phase high performance chromatography).
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Protein Sequence Analysis: Automated Microsequencing

Science, 1983
The automated microsequencing of proteins can now be carried out at the 5- to 10-picomoles (submicrogram) level on polypeptides obtained directly from one- and two-dimensional gel electrophoresis. The techniques are applicable to polypeptides ranging in size from small peptides (less than 10 residues) to large proteins (more than 1000 residues).
Hunkapiller, Michael W., Hood, Leroy E.
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New tools for protein sequence analysis

Trends in Biotechnology, 1990
Analysis of protein sequence is an important tool in studies of both native and recombinant proteins. Novel techniques and instrumentation which facilitate determination of protein primary structure have recently been developed.
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Solid-phase protein sequence analysis

Nature, 1990
The solutions to many protein analytical problems require flexible chemistries at a high sensitivity. Solid-phase sequence analysis is one way to eliminate limitations inherent in current methods.
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Analysis of sequence repeats of proteins in the PDB

Computational Biology and Chemistry, 2013
Internal repeats in protein sequences play a significant role in the evolution of protein structure and function. Applications of different bioinformatics tools help in the identification and characterization of these repeats. In the present study, we analyzed sequence repeats in a non-redundant set of proteins available in the Protein Data Bank (PDB).
David Mary Rajathei, Samuel Selvaraj
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Compact Protein Sequencer for the C-Terminal Sequence Analysis of Peptides and Proteins

Analytical Biochemistry, 1993
We describe the construction of a compact protein sequencer designed specifically for the C-terminal sequence analysis of peptides and proteins. This sequencer has a vertical flow path and is equipped with a continuous flow reactor (CFR). The flow paths for the various reagents and solvents have been minimized.
J M, Bailey, M, Rusnak, J E, Shively
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Chemical methods of protein sequence analysis

Journal of Chromatography A, 1995
Chemical methods of protein sequence determination are reviewed with particular emphasis on methodology for increasing the sensitivity of amino-terminal sequence analysis and on progress toward the development of an automated procedure for sequential degradation from the carboxy-terminus.
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Granular Approach for Protein Sequence Analysis

2012
Granular computing uses granules as basic units to compute with. Granules can be formed by either information abstraction or information decomposition. In this paper, we view information decomposition as a paradigm for processing data with complex structures.
Ying Xie 0001, Jonathan Fisher, Vijay V. Raghavan 0001, Tom Johnsten, Can Akkoç   +4 more
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Markov Analysis of Protein Sequence Similarities

2003
In our previous work, we explored the use of graph-theoretic spectral methods for clustering protein sequences [7]. The nodes of the graph represent a set of proteins to be clustered into families and/or super-families. Edges between nodes are undirected and weighted by the similarities between proteins. We constructed a novel similarity function based
Chakra Chennubhotla 0001, Alberto Paccanaro   +1 more
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PROTEAN: Protein Sequence Analysis and Prediction

Molecular Biotechnology, 2000
The archaeal, bacterial, andeukaryotic genome projects have overwhelmed our ability to experimentally elucidate the function of each novel gene and gene product. To a certain extent, protein functional assignments can be derived via sequence similarity measures and direct primary sequence analysis using methods to predict hydropathy, secondary ...
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