Results 251 to 260 of about 2,818,524 (302)

Computational Methods for Protein Sequence Analysis

Current Protocols in Protein Science, 1995
AbstractThis unit is presented as a guide to addressing the issue of what to do with a protein sequence once it is obtained. A theoretical background for protein sequence analysis is provided first, followed by a discussion of matrix methods for sequence comparison ().
G, Michaels, R, Garian
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Gene/Protein Sequence Analysis

2008
The advent of automated high throughput DNA sequencing methods has strongly enabled genome sequencing strategies, culminating in determination of the entire human genome (1,2). An enormous amount of DNA sequence data are available and databases still grow exponentially (see Fig. 22.1). Analysis of this overwhelming amount of data, including hundreds of
Rehm, BHA, Reinecke, F
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Protein Sequence Analysis by Proximities

2016
Sequence data are widely used to get a deeper insight into biological systems. From a data analysis perspective they are given as a set of sequences of symbols with varying length. In general they are compared using nonmetric score functions. In this form the data are nonstandard, because they do not provide an immediate metric vector space and their ...
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Computer analysis of protein sequences

1974
Most interesting of all of the biochemical components of living organisms are proteins and nucleic acids because of their potential for diversity in structure and function and their key positions in the evolutionary feedback system of each species. Sequence studies on these molecules have been carried out for various purposes in a number of disciplines:
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New tools for protein sequence analysis

Trends in Biotechnology, 1990
Analysis of protein sequence is an important tool in studies of both native and recombinant proteins. Novel techniques and instrumentation which facilitate determination of protein primary structure have recently been developed.
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Analysis of protein sequence similarity

2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010
This paper proposes a novel method for analyzing similarities of protein sequences based on features generated from the hydropathy properties of amino acid sequences. At first using the hydropathy characteristics, the protein sequences are converted into fixed-dimensional feature vectors. Based on these feature vectors, we analyze nine ND5 proteins and
null Yusen Zhang, null Xiangtian Yu
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Chemical methods of protein sequence analysis

Journal of Chromatography A, 1995
Chemical methods of protein sequence determination are reviewed with particular emphasis on methodology for increasing the sensitivity of amino-terminal sequence analysis and on progress toward the development of an automated procedure for sequential degradation from the carboxy-terminus.
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PROTEAN: Protein Sequence Analysis and Prediction

Molecular Biotechnology, 2000
The archaeal, bacterial, andeukaryotic genome projects have overwhelmed our ability to experimentally elucidate the function of each novel gene and gene product. To a certain extent, protein functional assignments can be derived via sequence similarity measures and direct primary sequence analysis using methods to predict hydropathy, secondary ...
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Sequence analysis of expressed proteins

1999
Abstract The generation of recombinant proteins may be considered a relatively facile process nowadays. The wide range of expression systems available, and the marketing of specialized molecular biological kits by a number of manufacturers, virtually ensure that reasonable quantities of recombinant proteins can be produced in most ...
Jeff N Keen, Alison E Ashcroft
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The chemistry of protein sequence analysis

2000
N-terminal sequence analysis by Edman chemistry continues to play an important role in the structural analysis of proteins and peptides. Improvements in the sensitivity of the method have been achieved mainly at the level of increasing the sensitivity of the on-line analysis of PTH amino acids by RP-HPLC (reverse phase high performance chromatography).
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