Results 251 to 260 of about 5,258,715 (348)

Missense variants pathogenicity annotation from homologous proteins. [PDF]

Bioinformatics
Ruiz-Alías G, Soldevila S, Altafaj X, Cordomí A, Olivella M.   +4 more
europepmc   +1 more source

Sequence analysis, expression, and binding activity of recombinant major outer sheath protein (Msp) of Treponema denticola

Journal of Bacteriology, 1996
J. Fenno, K. Müller, B. C. McBride
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Divergent molecular pathways govern temperature-dependent wheat stem rust resistance genes. [PDF]

Nat Commun
Hewitt TC, Sharma K, Zhang J, Chen C, Bajgain P, Bhatt D, Singh S, Olivera Firpo PD, Yang J, Wang Q, Upadhyaya N, Pozniak C, McIntosh R, Lagudah E, Zhang P, Rouse MN.   +15 more
europepmc   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Sequence analysis of the major outer membrane protein gene of Chlamydia pneumoniae

Infection and Immunity, 1991
Mercedes Perez Melgosa, C. Kuo, L A Campbell   +2 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Unifying sequence-structure coding for advanced protein engineering <i>via</i> a multimodal diffusion transformer. [PDF]

Chem Sci
Lin X, Chen Z, Li Y, Ma Z, Fan C, Cao Z, Feng S, Zhang J, Gao YQ.   +8 more
europepmc   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Design and evolution of a synthetic small protein scaffold based on the WW domain. [PDF]

Protein Sci
Dias AMGC, Teixeira GDG, Barbosa AJM, Goncalves J, Iranzo O, Roque ACA.   +5 more
europepmc   +1 more source