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Protein Sequence Analysis: Automated Microsequencing

Science, 1983
The automated microsequencing of proteins can now be carried out at the 5- to 10-picomoles (submicrogram) level on polypeptides obtained directly from one- and two-dimensional gel electrophoresis. The techniques are applicable to polypeptides ranging in size from small peptides (less than 10 residues) to large proteins (more than 1000 residues).
Hunkapiller, Michael W., Hood, Leroy E.
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Protein Sequence Analysis

2017
ExPASy (Expert Protein Analysis System) is a Bioinformatics Resource Portal from Swiss Institute of Bioinformatics that offers Bioinformatics support like accessing scientific databases and software tools for the research in life sciences.
Nachimuthu Senthil Kumar   +7 more
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Analysis of protein sequence similarity

2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010
This paper proposes a novel method for analyzing similarities of protein sequences based on features generated from the hydropathy properties of amino acid sequences. At first using the hydropathy characteristics, the protein sequences are converted into fixed-dimensional feature vectors. Based on these feature vectors, we analyze nine ND5 proteins and
Xiangtian Yu, Yusen Zhang
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Comparative sequence analysis in the sialyltransferase protein family: analysis of motifs.

Current Drug Targets, 2009
The sialyltransferase family represents a group of enzymes that transfers sialic acid from its common nucleotide sugar donor, CMP-NeuAc, to the terminal carbohydrates group of various glycoproteins and glycolipids. Cloning of these enzymes from mammalian
A. Datta
semanticscholar   +1 more source

Computer analysis of DNA and protein sequences

European Journal of Biochemistry, 1991
Some recent trends in the development of theoretical methods for DNA and protein sequence analysis are reviewed, with particular emphasis on the design of new databases, motif searches, sequence alignment algorithms and applications of neural networks.
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Hydrophobicity Profiles for Protein Sequence Analysis

Current Protocols in Protein Science, 1995
AbstractHydrophobic interactions are a major force in protein folding and numerous hydropathy scales have been developed to quantify the relative hydrophobicity of the amino acids. Hydropathy profiles can be used to examine the surface features of proteins in order to generate hypotheses that can be confirmed experimentally.
Jiri Novotny   +2 more
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New tools for protein sequence analysis [PDF]

open access: possibleTrends in Biotechnology, 1990
Analysis of protein sequence is an important tool in studies of both native and recombinant proteins. Novel techniques and instrumentation which facilitate determination of protein primary structure have recently been developed.
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Protein Sequence Analysis by Proximities

2016
Sequence data are widely used to get a deeper insight into biological systems. From a data analysis perspective they are given as a set of sequences of symbols with varying length. In general they are compared using nonmetric score functions. In this form the data are nonstandard, because they do not provide an immediate metric vector space and their ...
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Computational Methods for Protein Sequence Analysis

Current Protocols in Protein Science, 1995
AbstractThis unit is presented as a guide to addressing the issue of what to do with a protein sequence once it is obtained. A theoretical background for protein sequence analysis is provided first, followed by a discussion of matrix methods for sequence comparison ().
George S. Michaels, Robert Garian
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Computer analysis of protein sequences

1974
Most interesting of all of the biochemical components of living organisms are proteins and nucleic acids because of their potential for diversity in structure and function and their key positions in the evolutionary feedback system of each species. Sequence studies on these molecules have been carried out for various purposes in a number of disciplines:
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