Results 301 to 310 of about 31,098,092 (376)

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Social participation trajectories in late life and cognitive functioning - A sequence analysis based on Taiwan Longitudinal Study on aging. [PDF]

SSM Popul Health
Hsu YT, Hoven H, Grodstein F, Liu TH, Chang CR, Hsieh YL, Chen JT, Kawachi I.   +7 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Educational trajectories within and beyond the core education phase in Switzerland: a sequence analysis based on SHP data 1999-2023. [PDF]

Front Sociol
Edler S, Hadjar A.
europepmc   +1 more source

Modeling operator cognition for accident sequence analysis : development of an operator-plant simulation

, 1996
Vinh Ngoc Dang
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Frequency and Sequence Analysis of Echinococcus granulosus Sensu Lato Isolated From Buffaloes in Northern Iran. [PDF]

Vet Med Sci
Ghanbari F, Ashrafi K, Fasihi Harandi M, Abbaszadeh S, Ashouri A, Hajialilo E, Sharifdini M.   +6 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

16S rRNA Gene Sequence Analysis of V6-V8 Region Provides Limited Advantage in Diagnosis of Chronic Prostatitis. [PDF]

Diagnostics (Basel)
Rosellen J, Fritzenwanker M, Schuppe HC, Schagdarsurengin U, Wagenlehner F, Pilatz A.   +5 more
europepmc   +1 more source