Results 121 to 130 of about 3,380,352 (277)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

The genome sequence of Hyocomium armoricum (Brid.) Wijk & Margad. (Hypnales: Hypnaceae) [version 1; peer review: 2 approved]

Wellcome Open Research
We present a genome assembly of Hyocomium armoricum (Flagellate Feather-moss; Streptophyta; Bryopsida; Hypnales; Hypnaceae). The genome sequence has a total length of 333.60 megabases.
Elizabeth M. Kungu, David Bell, David G. Long, Gordon P. Rothero   +3 more
doaj   +1 more source

A Genome Sequence Assembly of the Phototactic and Optogenetic Model Fungus Blastocladiella emersonii Reveals a Diversified Nucleotide-Cyclase Repertoire. [PDF]

Genome Biol Evol, 2022
Leonard G, Galindo LJ, Milner DS, Avelar GM, Gomes-Vieira AL, Gomes SL, Richards TA.   +6 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Plant genome sequence assembly in the era of long reads: Progress, challenges and future directions. [PDF]

Quant Plant Biol, 2022
Pucker B, Irisarri I, de Vries J, Xu B.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Research on Parallel Assembly Sequence Planning of Vertical Planetary Gearboxes Based on the Ant Colony Algorithm

Jixie chuandong
The increase of parts in the assembly leads to the complexity of the assembly process and technology, the planning of the assembly sequence has become more rigorous, and the computer-aided assembly sequence planning has become an important direction of ...
Xu Wentao, Zhang Liyong, Zhi Yanfeng, Li Tongjie, Wang Juan, Wang Changlu, Jiang Yehu, Chen Jijie, Wang Wenxiang   +8 more
doaj  

Sequence, assembly and count datasets of viruses associated to the pine processionary moth Thaumetopoea pityocampa (Denis & Schiffermüller) (Lepidoptera, Notodontidae) identified from transcriptomic high-throughput sequencing. [PDF]

Data Brief, 2023
Dorkeld F, Streiff R, Sauné L, Castel G, Ogliastro M, Kerdelhué C.   +5 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

ContigExtender: a new approach to improving de novo sequence assembly for viral metagenomics data. [PDF]

BMC Bioinformatics, 2021
Deng Z, Delwart E.
europepmc   +1 more source