Results 81 to 90 of about 3,380,352 (277)
Phylogenetic Comparative Assembly [PDF]
, 2009 Husemann P, Stoye J. Phylogenetic Comparative Assembly. Algorithms for Molecular Biology. 2010;5(1): 3.BACKGROUND:Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects ...
Stoye Jens +5 more
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Wellcome Open ResearchWe present a genome assembly of Gnaphalium uliginosum (marsh cudweed; Streptophyta; Magnoliopsida; Asterales; Asteraceae). The genome sequence has a total length of 354.38 megabases.
Maarten J. M. Christenhusz
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Wellcome Open ResearchWe present a genome assembly of Viola odorata (Sweet violet; Streptophyta; Magnoliopsida; Malpighiales; Violaceae). The genome sequence has a total length of 698.62 megabases. Most of the assembly (99.9%) is scaffolded into 10 chromosomal pseudomolecules.
Maarten J. M. Christenhusz +2 more
doaj +1 more source
Auto Sequencer: A DNA Sequence Alignment and Assembly Tool
Spectrum, 2018 The process of determining the exact order of nucleotides in DNA is a crucial component of a wide variety of research applications known as DNA sequencing.
Abhi Aggarwal +2 more
doaj +1 more source
Sequence-Controlled Polymerization-Induced Self-Assembly
, 2019 We herein present sequence-controlled polymerization-induced self-assembly (PISA) via photoswitchable reversible addition–fragmentation chain transfer (RAFT) copolymerization of oppositely-charged monomers using polyethylene glycol chain transfer agent ...
Yi Ding (172783) +13 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Wellcome Open ResearchWe present a genome assembly of Cardamine flexuosa (Wavy Bitter-cress; Streptophyta; Magnoliopsida; Brassicales; Brassicaceae). The genome sequence has a total length of 204.54 megabases.
Maarten J. M. Christenhusz
doaj +1 more source