Results 171 to 180 of about 5,890,604 (383)

DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets.

Molecular biology and evolution, 2017
J. Rozas, Albert Ferrer-Mata, Juan C. Sánchez-DelBarrio, S. Guirao-Rico, P. Librado, S. Ramos-Onsins, A. Sánchez‐Gracia   +6 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Inferences on the evolution of the ascorbic acid synthesis pathway in insects using Phylogenetic Tree Collapser (PTC), a tool for the automated collapsing of phylogenetic trees using taxonomic information

Journal of Integrative Bioinformatics
When inferring the evolution of a gene/gene family, it is advisable to use all available coding sequences (CDS) from as many species genomes as possible in order to infer and date all gene duplications and losses.
Glez-Peña Daniel, López-Fernández Hugo, Duque Pedro, Vieira Cristina P., Vieira Jorge   +4 more
doaj   +1 more source

Elaboração e validação de sequências didáticas sobre ecologia e conservação da fauna para o ensino de biologia / Preparation and validation of teaching sequences on ecology and fauna conservation for the teaching of biology

, 2021
Marcos Anjos De Moura, Maurício de Oliveira Silva, Thomas Leonardo Marques de Castro Leal   +2 more
openalex   +1 more source

Where Biology and Traditional Polymers Meet: The Potential of Associating Sequence-Defined Polymers for Materials Science [PDF]

, 2021
Audra J. DeStefano, Rachel A. Segalman, Emily Davidson   +2 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Cells, shared memory and breaking the PTM code

Molecular Systems Biology, 2012
Pau Creixell, Rune Linding
doaj   +1 more source

Protocol for mitochondrial DNA isolation from Macrobrachium rosenbergii and Penaeus monodon using differential centrifugation

STAR Protocols
Summary: The mitochondrial genome (mitogenome) is a vital tool in molecular phylogenetics, evolutionary biology, and population genetics. Here, we present a protocol for extracting mitochondrial DNA from shrimp (Macrobrachium rosenbergii) and prawn ...
Dipta Chandra Pal, Muhammad Manjurul Karim   +1 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Sequence Data Analysis Guidebook. Methods in Molecular Biology, Volume 70. Edited by Simon R. Swindell. Humana Press, 1997. 324 pages. Price $69.50. ISBN 0 89603 358 9. [PDF]

, 1997
Andrew Coulson
openalex   +1 more source