Results 171 to 180 of about 4,751,605 (346)

Biology and Genome Sequence of Streptococcus mutans Phage M102AD

, 2012
Allan L. Delisle, Ming Guo, Natalia I. Chalmers, G J Barcak, Geneviève M. Rousseau, Sylvain Moineau   +5 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Corrigendum to “Real-time recognition of patient intentions from sequences of pressure maps using artificial neural networks” [Computers in Biology and Medicine 42 (2012) 364–375]

, 2013
Manuel Chica, Pascual Campoy, María Ana Pérez, Tomás Escobar Rodríguez, Rubén Rodríguez, Óscar Valdemoros   +5 more
openalex   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

A digital DNA system favours the superiority of unidirectional inheritance over 'Lamarckian' inheritance. [PDF]

PLoS Comput Biol
Shiju A, Arras SDM, Rodrigo AG, Poole AM.   +3 more
europepmc   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

wavess: An R package for simulation of adaptive within-host virus sequence evolution. [PDF]

PLoS Comput Biol
Sambaturu N, Lapp Z, Tria FDK, Romero-Severson E, Molina-París C, Leitner T.   +5 more
europepmc   +1 more source

Functional Analysis of the Brca1 H1686Q Sequence Variant: from Biology to Clinic

, 2014
Arcangela De Nicolo, Anita Giobbie‐Hurder, Shailja Pathania, Emilio Parisini, Rebecca Gelman, John A. A. Ladias, Vladimir Joukov   +6 more
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

The Role of AI-Driven De Novo Protein Design in the Exploration of the Protein Functional Universe. [PDF]

Biology (Basel)
Zhang G, Liu C, Lu J, Zhang S, Zhu L.
europepmc   +1 more source