Results 171 to 180 of about 1,220,765 (311)

1E1312 P71 Whole genome resequencing of experimentally evolved Escherichia coli using a next generation sequencer(Genome biology, Bioinformatics,The 49th Annual Meeting of the Biophysical Society of Japan)

, 2011
Naoaki Ono, Takaaki Horinouchi, Kuniyasu Tamaoka, Shingo Suzuki, Takashi Hirasawa, Chikara Furusawa, Tetsuya Yomo, Hiroshi Shimizu   +7 more
openalex   +2 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Corrigendum to “Real-time recognition of patient intentions from sequences of pressure maps using artificial neural networks” [Computers in Biology and Medicine 42 (2012) 364–375]

, 2013
Manuel Chica, Pascual Campoy, María Ana Pérez, Tomás Escobar Rodríguez, Rubén Rodríguez, Óscar Valdemoros   +5 more
openalex   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Gauge fixing for sequence-function relationships. [PDF]

PLoS Comput Biol
Posfai A, Zhou J, McCandlish DM, Kinney JB.   +3 more
europepmc   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

Functional Analysis of the Brca1 H1686Q Sequence Variant: from Biology to Clinic

, 2014
Arcangela De Nicolo, Anita Giobbie‐Hurder, Shailja Pathania, Emilio Parisini, Rebecca Gelman, John A. A. Ladias, Vladimir Joukov   +6 more
openalex   +1 more source

Molecular biology: CACA sequences — the ends and the means? [PDF]

, 1983
John Rogers
openalex   +1 more source

Bioinformatics analysis and development of functional markers for TaMYB4-1A in wheat. [PDF]

PLoS One
Zhao D, Ma Y, Yang Y, Li Z, Wang C, Fu Y, Chen Y, Zhang T, Ding Y, Wang H, Zhang X, Zhang H.   +11 more
europepmc   +1 more source