Results 61 to 70 of about 1,118,063 (263)
On optimal operational sequence of components in a warm standby system
Abstract We consider an open problem of obtaining the optimal operational sequence for the 1-out-of-n system with warm standby. Using the virtual age concept and the cumulative exposure model, we show that the components should be activated in accordance with the increasing sequence of their lifetimes.
Maxim Finkelstein +2 more
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
To analyze unbalanced electrical systems, the mathematical technique “symmetrical components method” developed by Charles LeGeyt Fortescue in the early 20th century has been very successful in this field.
Karim Mansouri +4 more
doaj +1 more source
Unified Modeling Language Quantitative Measures Based on a Behavioural Model [PDF]
Behavioral diagrams in Unified Modeling Language reflect the interaction between system components and give a comprehensive description and visualization of the system during the design phase. One of the most important behavioral diagrams is the sequence
Marwah Dabdawb
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Algorithm of Equivalent Inter-phase Impedance for Three-phase Unbalanced Loads and Its Applications
It presented a method for calculating equivalent inter-phase impedance of three-phase unbalanced loads in three-phase three-wire system. Phase voltages and line currents of unbalanced system were decomposed into positive sequence and negative sequence ...
ZHU Mingxing +4 more
doaj
The widespread integration of inverter-based distributed generators (IIDGs) severely limits the adaptability of conventional three-step overcurrent protection in distribution networks (DNs).
Shi Su +8 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

