Peptide turnover prediction using transformer architectures on large-scale time-series proteomic data. [PDF]
Ishino K, Yoshizawa AC, Liu Y, Okuda S.
europepmc +1 more source
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source
A circovirus-like genomic sequence with unique architecture and phylogenetic relatedness to human-linked viral lineages. [PDF]
Dai L +11 more
europepmc +1 more source
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Multi-clade co-evolution and differential replication efficiencies of subgroup A avian leukosis virus in Chinese guinea fowl. [PDF]
Chen J +8 more
europepmc +1 more source
Properties and N-Terminal amino acid sequences of three Erythrina lectins from Costa Rica (Leguminosae) [PDF]
Aragón-Ortiz, Federico +2 more
core
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Homology Modeling of Type-P5 ATPases from the Malaria Parasite: Insight into Their Functions and Evolution, and Implications About the Effect and Role of Intrinsically Disordered Protein Structure. [PDF]
Wiser MF.
europepmc +1 more source

