Results 61 to 70 of about 104,871 (266)

Equine Multinodular Pulmonary Fibrosis Associated with Equine Herpesvirus 5 in a Horse in Brazil

Brazilian Journal of Veterinary Pathology, 2014
This report describes the first diagnosed case of equine multinodular pulmonary fibrosis associated with equine herpesvirus 5 (EHV-5) in a horse in Brazil.
Welden Panziera, Paula R. Giaretta, Glauco J. N. Galiza, Ailam Lim, Steven R. Bolin, Carlos H. Borges, Rafael A. Fighera, Claudio S. L. Barros   +7 more
doaj   +1 more source

Experimental and Natural Infections of Goats with Severe Fever with Thrombocytopenia Syndrome Virus: Evidence for Ticks as Viral Vector. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:Severe fever with thrombocytopenia syndrome virus (SFTSV), the causative agent for the fatal life-threatening infectious disease, severe fever with thrombocytopenia syndrome (SFTS), was first identified in the central and eastern regions of ...
Yongjun Jiao, Xian Qi, Dapeng Liu, Xiaoyan Zeng, Yewu Han, Xiling Guo, Zhiyang Shi, Hua Wang, Minghao Zhou   +8 more
doaj   +1 more source

Complete amino acid sequence of the nucleic acid-binding protein of bovine leukemia virus

, 1983
The complete amino acid sequence of the nucleic acid-binding protein p12 of bovine leukemia virus (BLV) has been determined. Peptides were generated by enzymatic digestion and formic acid cleavage, purified by reversed-phase liquid chromatography and ...
Copeland, Terry D., Stephen Oroszlan, Morgan, M.Alice, M.Alice Morgan, Oroszlan, Stephen, Terry D. Copeland   +5 more
core   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology [PDF]

, 2010
Conventional drug design embraces the "one gene, one drug, one disease" philosophy. Polypharmacology, which focuses on multi-target drugs, has emerged as a new paradigm in drug discovery.
Chen Zhijun, Rommie E. Amaro, Wunder Frank, Michael D. Urbaniak, Philip E. Bourne, Amaro, Rommie E., McCammon, J. Andrew, Urbaniak, Michael D., Michael D Urbaniak, Lei Xie, Michael A J Ferguson, Wunder, Frank, Ferguson Michael A. J., Jacob D. Durrant, Jacob D Durrant, Di Guilmi, Anne Marie, Zhijun Chen, Haapalainen Antti, Urbaniak Michael D., McCammon J. Andrew, J Andrew McCammon, Durrant, Jacob D., Xie, Lei, Rommie E Amaro, Chen, Zhijun, Ferguson, Michael A. J.; id_orcid, Frank Wunder, Amaro Rommie E., Bourne Philip E., Antti Haapalainen, Durrant Jacob D., J. Andrew McCammon, Di Guilmi Anne Marie, Michael A. J. Ferguson, Xie Lei, Bourne, Philip E., Ferguson, Michael A. J., Haapalainen, Antti, Anne Marie Di Guilmi, Philip E Bourne   +39 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Molecular detection of Citrus exocortis viroid (CEVd), Citrus viroid-III (CVd-III), and Citrus viroid-IV (CVd-IV) in Palestine

Scientific Reports
Citrus hosts various phytopathogens that have impacted productivity, including viroids. Missing data on the status of viroids in citrus in Palestine were not reported.
Aswar Abualrob, Osama Alabdallah, Raied Abou Kubaa, Sabri M. Naser, Raed Alkowni   +4 more
doaj   +1 more source

Traceability analysis of a foodborne disease outbreak caused by Clostridium perfringens in Ma’anshan City, Anhui Province, 2024

Frontiers in Public Health
ObjectivesThis study aimed to perform laboratory testing and traceability analysis of suspicious samples from a foodborne disease outbreak caused by Clostridium perfringens (C. perfringens) in a hospital in Ma’anshan City, Anhui Province, and to evaluate
Li Wang, Ying Luo, Yuanting Sun, Fen Lu, Yiqun Chen, Liangliang Jiang   +5 more
doaj   +1 more source

Intragenic tandem repeats in Daphnia magna: structure, function and distribution [PDF]

, 2009
Background Expressed sequence tag (EST) databases provide a valuable source of genetic data in organisms whose genome sequence information is not yet compiled.
Ebert, Dieter, Dieter Ebert, Du Pasquier Louis, Du Pasquier, L., Ebert Dieter, Colson, I., Colson Isabelle, Isabelle Colson, Louis Du Pasquier   +8 more
core   +1 more source

Allosteric DNAzyme‐Enabled Sensitive and Multiplex Detection of Biomarkers for Rapid Diagnosis of Urinary Tract Infections

Advanced Science, EarlyView.
A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen, Chenzhi Shi, Xiaowei Ma, Pengfei Hou, Haomin Zhang, Juanxiu Qin, Li Pan, Guilin Li, Lifei Gao, Qian Ma, Donglei Yang, Min Li, Pengfei Wang   +12 more
wiley   +1 more source