Results 21 to 30 of about 8,935,685 (345)

Efficient Exploration of Sequence Space by Sequence-Guided Protein Engineering and Design.

open access: yesBiochemistry, 2022
The rapid growth of sequence databases over the past two decades means that protein engineers faced with optimizing a protein for any given task will often have immediate access to a vast number of related protein sequences.
B. Clifton, Dan Kozome, P. Laurino
semanticscholar   +1 more source

Measure of noncompactness for an infinite system of fractional Langevin equation in a sequence space

open access: yes, 2021
A new sequence space related to the space ℓ p $\ell _{p}$ , 1 ≤ p < ∞ $1\leq ...
A. Salem   +2 more
semanticscholar   +1 more source

Fractional Cesàro Matrix and its Associated Sequence Space

open access: yesConcrete Operators, 2021
In this research, we introduce a new fractional Cesàro matrix and investigate the topological properties of the sequence space associated with this matrix.We also introduce a fractional Gamma matrix aswell and obtain some factorizations for the Hilbert ...
Roopaei H., İlkhan M.
doaj   +1 more source

Population Disequilibrium as Promoter of Adaptive Explorations in Hepatitis C Virus

open access: yesViruses, 2021
Replication of RNA viruses is characterized by exploration of sequence space which facilitates their adaptation to changing environments. It is generally accepted that such exploration takes place mainly in response to positive selection, and that ...
Carlos García-Crespo   +13 more
doaj   +1 more source

A Genome of Temperate Enterococcus Bacteriophage Placed in a Space of Pooled Viral Dark Matter Sequences

open access: yesViruses, 2023
In the human gut, temperate bacteriophages interact with bacteria through predation and horizontal gene transfer. Relying on taxonomic data, metagenomic studies have associated shifts in phage abundance with a number of human diseases.
Ivan M. Pchelin   +7 more
doaj   +1 more source

Exploring Protein Sequence Space Using Computationally Directed Recombination [PDF]

open access: yes, 2006
Evolution has provided us with many protein sequences. However, these sequences represent a very small fraction of the possible sequences. In the laboratory, scientists have explored areas of sequence space not represented by natural proteins both to ...
Meyer, Michelle Margaret
core   +1 more source

Attenuation of Avian Flavivirus by Rewiring the Leucine and Serine Codons of Its E-NS1 Protein toward Stop Mutation To Redirect Virus Evolution

open access: yesMicrobiology Spectrum, 2023
Recently, a new strategy for attenuating RNA viruses by redirecting their evolution in sequence space was confirmed for Enterovirus and Influenza viruses.
Jiaqi Guo   +19 more
doaj   +1 more source

Solvability of an infinite system of integral equations on the real half-axis

open access: yesAdvances in Nonlinear Analysis, 2020
The aim of the paper is to investigate the solvability of an infinite system of nonlinear integral equations on the real half-axis. The considerations will be located in the space of function sequences which are bounded at every point of the half-axis ...
Banaś Józef, Woś Weronika
doaj   +1 more source

Upper Bound of Difference Operator on Some Matrix Domains

open access: yesJournal of Mathematical Sciences and Modelling, 2021
In this study, we investigate the norm of difference operator on some sequence spaces such as Hilbert and Cesaro matrix domains. Therefore the present study is a complement for those results obtained in [1].
Maryam Sinaei, Lotfollah Karimi
doaj   +1 more source

Binomial difference sequence spaces of order m

open access: yesAdvances in Difference Equations, 2017
In this paper, we introduce the binomial sequence spaces b 0 r , s ( ∇ ( m ) ) $b^{r,s}_{0}(\nabla^{(m)})$ , b c r , s ( ∇ ( m ) ) $b^{r,s}_{c}(\nabla^{(m)})$ and b ∞ r , s ( ∇ ( m ) ) $b^{r,s}_{\infty}(\nabla^{(m)})$ by combining the binomial ...
Jian Meng, Meimei Song
doaj   +1 more source

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