Results 71 to 80 of about 894,223 (229)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Some generalized difference double sequence spaces defined by a sequence of Orlicz-functions

open access: yesCubo, 2012
In the present paper we introduce some generalized difference double sequence spaces defined by a sequence of Orlicz-functions. We study some topological properties and some inclusion relations between these spaces.
Kuldip Raj, Sunil K Sharma
doaj  

Some New Cauchy Sequence Spaces

open access: yesUniversal Journal of Mathematics and Applications, 2018
In this paper, our goal is to introduce some new Cauchy sequence spaces. These spaces are defined by Cauchy transforms. We shall use notations $C_{\infty }\left( s,t\right) $, $C\left( s,t\right) $ and $C_{0}\left( s,t\right) ~$for these new sequence ...
Harun Polat
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

New Sequence Spaces Generated via a Matrix Defined by Schröder and Catalan Numbers [PDF]

open access: yesSahand Communications in Mathematical Analysis
This study introduces the sequence spaces $c(S^\star)$ and $c_0(S^\star)$, defined as the domain of the matrix $S^\star$ constructed from a hybrid structure involving Schr\"{o}der and Catalan numbers.
Hacer Bilgin Ellidokuzoğlu   +2 more
doaj   +1 more source

Diagonal Multilinear Operators on K\"othe Sequence Spaces

open access: yes, 2017
We analyze the interplay between maximal/minimal/adjoint ideals of multilinear operators (between sequence spaces) and their associated K\"othe sequence spaces.
Dimant, Verónica, Villafañe, Román
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Compactness via Hausdorff measure of non-compactness and some properties on Tetranacci sequence spaces

open access: yesDera Natung Government College Research Journal
The characterization of compact operators on BK-spaces, which is the basis of this research, makes use of the Hausdorff measure of non-compactness. In this study, the compactness criteria of matrix operators defined on BK-spaces $\ell_p(\mathcal{T})$ and
Sezer Erdem, Serkan Demiriz
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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