Results 51 to 60 of about 2,731,359 (291)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Summability factors between the absolute Cesàro methods
If Σε_{n}x_{n} is summable by the method Y whenever Σx_{n} is summable by the method X, then we say that the factor ε=(ε_{n}) is of type (X,Y) and denote by (X,Y).
G. Canan Hazar Güleç
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
This journal is the product of a collective effort. A great deal of work went into its publication, for which we are all very grateful. First, thank you to Melanie Lintott for creating the cover image that so perfectly encapsulates the themes this ...
Between, Spaces
core
A Note On The Series Space |N ̅_p^θ |(μ)
The series space$\left\vert \bar{N}_{p}^{\theta }\right\vert\left( \mu \right) $has recently been introduced and studied by Gökçe and Sarıgöl [1]. Themain purpose of this paper is to determine the $\alpha-$,$\beta-$and$\gamma$_duals of the space and to ...
Fadime Gökçe
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
In this paper we define the space co(Δ)={x=(xk)/xk−kk−1→0(k→∞),xo=0,xk∈ℂ} and compute its duals (Continuous dual, β-dual and N-dual) The aim of this paper is to give same results about matrix mapping of co(Δ) into other sequence spaces including the ...
Hüsnü Kizmaz
doaj +1 more source
Bekanntlich heißt ein Raum \(E\) von komplexwertigen Folgen \(x=(x_ n)\) solid, wenn gilt: \(x\in E\;\&\;| y_ n|\leq| x_ n|\), \((n\in\mathbb{N})\Rightarrow y\in E\). Diese Eigenschaft läßt sich auf vektorwertige Folgenräume in verschiedene Richtungen verallgemeinern. Für einen normierten Raum \(X\) bezeichne \(s(X)\) den Raum aller Folgen \(x=(x_ n)\)
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

