Results 31 to 40 of about 894,223 (229)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A note on Köthe-Toeplitz duals of certain sequence spaces and their matrix transformations

International Journal of Mathematics and Mathematical Sciences, 1995
In this paper we define the sequence spaces Sℓ∞(p), Sc(p) and Sc0(p) and determine the Köthe-Toeplitz duals of Sℓ∞(p). We also obtain necessary and sufficient conditions for a matrix A to map Sℓ∞(p) to ℓ∞ and investigate some related problems.
B. Choudhary, S. K. Mishra
doaj   +1 more source

Delay Differential Equations in Sequence Spaces

Communications in Advanced Mathematical Sciences, 2019
The standard  delay equations are newly studied in the context of classical separable Banach Sequence Spaces.  As a classical solution is shown to exist, the associated semigroup and its infinitesimal generator are found, and some important properties of
Luis Gerardo Mármol, Carmen Judith Vanegas   +1 more
doaj   +1 more source

Iterated Differential Forms V: C-Spectral Sequence on Infinite Jet Spaces

, 2007
In the preceding note math.DG/0610917 the $\Lambda_{k-1}\mathcal{C}$--spectral sequence, whose first term is composed of \emph{secondary iterated differential forms}, was constructed for a generic diffiety.
Vinogradov, A. M., Vitagliano, L.
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Coarse and uniform embeddings between Orlicz sequence spaces

, 2013
We give an almost complete description of the coarse and uniform embeddability between Orlicz sequence spaces. We show that the embeddability between two Orlicz sequence spaces is in most cases determined only by the values of their upper Matuszewska ...
F Albiac, I Aharoni, L Borel-Mathurin, M Mendel, Michal Kraus, N.J. Kalton, N.J. Kalton, N.J. Kalton, N.L. Randrianarivony, P.W. Nowak, P.W. Nowak, W.B. Johnson   +11 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source