Results 111 to 120 of about 2,334,123 (318)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Gram-Negative ESKAPE Bacteria Surveillance in COVID-19 Pandemic Exposes High-Risk Sequence Types of Acinetobacter baumannii MDR in a Tertiary Care Hospital

Pathogens
The interruption of bacteriological surveillance due to the COVID-19 pandemic brought serious consequences, such as the collapse of health systems and the possible increase in antimicrobial resistance.
Mónica Alethia Cureño-Díaz, Estibeyesbo Said Plascencia-Nieto, Miguel Ángel Loyola-Cruz, Clemente Cruz-Cruz, Andres Emmanuel Nolasco-Rojas, Emilio Mariano Durán-Manuel, Gabriela Ibáñez-Cervantes, Erika Gómez-Zamora, María Concepción Tamayo-Ordóñez, Yahaira de Jesús Tamayo-Ordóñez, Claudia Camelia Calzada-Mendoza, Juan Manuel Bello-López   +11 more
doaj   +1 more source

Impact of an electric field on P-type ATPases [PDF]

, 2008
P-type ATPases are membrane proteins acting as ion pumps that drive an active transport of cations across the membrane against a concentration gradient. The required energy for the ion transport is provided by binding and hydrolysis of ATP.
Weidemüller, Christian, Hauser, Karin
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Extraintestinal traits of pathogenicity and sequence type lineages in commensal Escherichia coli from adults and young children: genotypic and phenotypic profiles

Frontiers in Microbiology
BackgroundThe commensal Escherichia coli population may significantly influence the pathogenesis of extraintestinal infections. The assignment to specific sequence type (ST) lineages and the presence of particular combinations of virulence genes are ...
Ewa Bok, Justyna Mazurek-Popczyk, Magdalena Wojciech, Katarzyna Baldy-Chudzik   +3 more
doaj   +1 more source

Sequence Types for the π-calculus

Electronic Notes in Theoretical Computer Science, 2005
AbstractWe introduce channel sequence types to study finitary polymorphism in the context of mobile processes modelled in the π-calculus. We associate to each channel a set of exchange types, and we require that output processes send values of one of those types, and input processes accept values of any type in the set.
openaire   +1 more source

Bovine rotavirus V1005 a P5, not a P12, type like all viruses in a German survey [PDF]

, 1994
Bovine rotavirus (BRV) V1005, like 34 further cell culture-adapted strains in a 6-year survey in Upper Bavaria, Germany, is not a P12 but a P5 P-type rotavirus.
Sidoti, Josette, Eichhorn, Werner, Nakagomi, Osamu, Büssow, Harald, Rohwedder, Angela   +4 more
core  

Application of MLST and Pilus gene sequence comparisons to investigate the population structures of Actinomyces naeslundii and Actinomyces oris [PDF]

, 2011
Actinomyces naeslundii and Actinomyces oris are members of the oral biofilm. Their identification using 16S rRNA sequencing is problematic and better achieved by comparison of metG partial sequences. A.
Radford, David R., Beighton, D., Gilbert, Steven C., David R Radford, Gilbert, S.C., Wickström, Claes, Cox, Steven, David Beighton, Radford, D.R., Steven C Gilbert, Clark Douglas, Cox Steven, Do, T, Henssge, Uta, Wickstrom, C., Ligtenberg, A. J. M., Clark, D., A. J. M. Ligtenberg, Henssge, U., Do, Thuy, Thuy Do, Henssge Uta, Uta Henssge, David R. Radford, Clark, Douglas, Wickström, Claes,, Henssge, U, Ligtenberg, A.J.M., Gilbert, SC, Cox, S., Do, T., Wickström Claes, Wickstroem, Claes, Ligtenberg A. J. M., Beighton, D, Radford, DR, Beighton, David, Ligtenberg, A., Gilbert Steven C., Beighton David, Douglas Clark, Steven Cox, Ligtenberg, Antoon J. M., Steven C. Gilbert, Cox, S, A J M Ligtenberg, Ligtenberg, AJM, Gilbert, S., Wickström, C, Do, Ngoc Thanh Thuy, Do Thuy, Clark, D, Ligtenberg, A.J.M.; id_orcid, Radford David R., Claes Wickström   +54 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source