Results 231 to 240 of about 2,333,875 (318)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Fatal bacteremia caused by novel sequence type 1665 of non-O1/non-O139 Vibrio cholerae: a case report and literature review. [PDF]

BMC Infect Dis
Wang Y, Luo Y, Zhang W, Chen X, Wu Q.
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

<i>qacA</i> is a key factor in heteroresistance to vancomycin in sequence type 5 methicillin-resistant <i>Staphylococcus aureus</i> isolates from pneumonia patients. [PDF]

Microbiol Spectr
Zhang K, Xi L, Bian Q, Yin Y, Chen M, Yang P, Chen Z, Wu H, Zhu Y, Zheng H, Chen D, Fan Y, Zhang J.   +12 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Shifting of bla_KPC-2 to bla_KPC-90 in a sequence type 11 Klebsiella pneumoniae strain before the use of ceftazidime-avibactam. [PDF]

BMC Genomics
Hu D, Zhao Y, Mi S, Wang S, Zhang J, Luo X, Li D, Chen J, Hong G.   +8 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Rectal Carriage of Sequence Type 307 Klebsiella pneumoniae High-Risk Clone Harboring Multiple Carbapenemase Genes in Community Hospitals Gauteng, South Africa. [PDF]

Microbiologyopen
Salvador-Oke KT, Pitout J, Peirano G, Strydom KA, Kingsburgh C, Ehlers M, Kock M.   +6 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Community-associated quinolone-resistant and extended-spectrum beta-lactamase-producing <i>Escherichia coli</i> isolates are similar to clinical infection isolates by sequence type and resistome. [PDF]

mSystems
Benedict EE, Agee W, Hink T, Parrish KL, Reske KA, Peacock K, Bosserman RE, Valencia A, Saluja A, Ovchiyan E, Arter O, Jolani K, Dubberke ER, Dantas G, Kwon JH.   +14 more
europepmc   +1 more source