Results 181 to 190 of about 1,430,679 (327)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Machine learning for enzyme catalytic activity: current progress and future horizons. [PDF]

Brief Bioinform
Qiu S, Saeed H, Leonard W, Li F, Yang A.
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Cultural Transmission Promotes the Emergence of Statistical Properties That Support Language Learning. [PDF]

Cogn Sci
Wolters L, Kirby S, Arnon I.
europepmc   +1 more source

Generation of Sets of Sequences lsomorphic to Walsh Sequences

, 2005
Walsh sequences of the order 2k, k positive integer, form an additive group generated by Rademacher sequences set of ft-order. Except the zero sequence, Walsh sequences form an orthogonal set. Our present work allows us to generate 2r-' sets of sequences.
openaire   +1 more source

LOESS correction for length variation in gene set-based genomic sequence analysis [PDF]

, 2012
Anton Aboukhalil, Martha L. Bulyk
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Exploring the Boundaries of Modern Quantum Annealers with RNA Structure Prediction. [PDF]

J Phys Chem B
Andrews B, Abraham J, Fox D, Radja A.
europepmc   +1 more source

Expanding the Mircea Set: A Grammatical Synthesis of Dynamic Flows and Dragon Sequences

Vlasie Catalin Mircea
openalex   +1 more source

The Milanova Sequence and Cantor’s Diagonal Argument: A Quantum Leap in Set Theory and Applications

, 2023
Pavel Cherkashin
openalex   +2 more sources