Results 161 to 170 of about 1,873,067 (319)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Nanopore direct RNA sequencing for RNA modification analysis: workflow assessment and computational tool benchmarking. [PDF]
Wu Z +6 more
europepmc +1 more source
Whole genome sequencing based differentiation between re-infection and relapse in Indian patients with tuberculosis recurrence, with and without HIV co-infection [PDF]
Sivakumar Shanmugam +10 more
openalex +1 more source
Creative sequences and double sequences.
openaire +2 more sources
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Assessing sequencing-based pathogen surveillance of a recreational swimming area in Oslo, Norway. [PDF]
Eldholm V, Straume D, Brynildsrud OB.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cloning, sequencing and expression of the lipase gene from Pseudomonas fragi IFO‐12049 in E. coli [PDF]
Shigeyuki Aoyama +2 more
openalex +1 more source

