Results 201 to 210 of about 1,873,067 (319)

Diagnostic sensitivity and specificity of metagenomic sequencing and qPCR for detection of viruses associated with bovine respiratory disease estimated using Bayesian latent class models. [PDF]

Front Vet Sci
Donbraye E, McLeod L, Chai Z, Lacoste SR, McCarthy EL, Hill JE, Erickson NEN, Links MG, Otto SJG, Huang Y, Waldner CL.   +10 more
europepmc   +1 more source

Human genomics of acute liver failure due to hepatitis B virus infection: an exome sequencing study in liver transplant recipients [PDF]

, 2018
Samira Asgari, Nimisha Chaturvedi, Petar Šćepanović, Christian Hammer, Nasser Semmo, Emiliano Giostra, Beat Müllhaupt, Peter Angus, Alexander Thompson, Darius Moradpour, Jacques Fellay   +10 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

DoBSeqWF: a framework for sensitive detection of individual genetic variation in pooled sequencing data. [PDF]

NAR Genom Bioinform
Cort Nielsen M, Hagen CM, Stoltze UK, Hansen TVO, Nyegaard M, Hjalgrim H, Bækvad-Hansen M, Byrjalsen A, Schmiegelow K, Wadt K, Bybjerg-Grauholm J, Rasmussen S.   +11 more
europepmc   +1 more source

Evolving Sequences [PDF]

Nature New Biology, 1971
openaire   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning. [PDF]

Synth Syst Biotechnol
Li X, Zheng Y, Shao Q, Wang J, Li W, Wang B, Zhou S, Cao B, Zheng P.   +8 more
europepmc   +1 more source

TABLE 4 from Real-world Trends, Rural-urban Differences, and Socioeconomic Disparities in Utilization of Narrow versus Broad Next-generation Sequencing Panels

Yiqing Zhao, Anastasios Dimou, Zachary C. Fogarty, Jun Jiang, Hongfang Liu, William B. Wong, Chen Wang   +6 more
openalex   +1 more source

Mycetoma of the Foot Caused byFusarium solani: Identification of the Etiologic Agent by DNA Sequencing

, 2003
Hélène Yera, Marie‐Elisabeth Bougnoux, C. Jeanrot, M.-T. Baixench, Gonzague de Pinieux, Jean Dupouy‐Camet   +5 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source