Results 91 to 100 of about 25,817 (283)
Logical inferentialism is the view that the meaning of logical constants is implicitly defined by the operational rules that govern their behaviour in proofs—particularly in sequent calculus proofs, according to an increasingly dominant tendency.
Bogdan Dicher, Francesco Paoli
doaj +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Sequent calculi and quasivarieties
Summary: We discuss relatively point-regular quasivarieties related in some special sense to sequent calculi. We show that the free algebra in such a quasivariety is Fregean iff in the sequent calculus the so-called symmetric contraction rules are admissible. In the presence of the fusion connective this is equivalent to having contraction.
openaire +3 more sources
Free variable sequent calculi [PDF]
This is a thesis about free variable sequent calculi for first-order languages without equality. A brief summary: Chapter 1 and 2 are mainly background material.
Antonsen, Roger
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
SEQUENT CALCULI FOR FINITE VALUED LUKASIEWICZ LOGICS VIA BOOLEAN DECOMPOSITIONS
In this paper we define internal cut-free sequent calculi for any n-valued Lukasiewicz logic Ln. These calculi are based on a representation of formulas of Ln, by n - 1 many {0, 1}-valued formulas of Ln. They enjoy the usual properties of sequent systems
CIABATTONI A. +5 more
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Sequent Calculi for the Normal Terms of the -a n d -Calculi ?
. This paper presents two sequent calculi, requiring no clausal form for types, whose typable terms are in 1-1 correspondence with the normal terms of the -a n d -calculi.
Roy Dyckho, Lu S Pinto
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

