Results 41 to 50 of about 49,363 (243)
Automatic Parallelization: Executing Sequential Programs on a Task-Based Parallel Runtime
, 2016 There are billions of lines of sequential code inside nowadays' software which do not benefit from the parallelism available in modern multicore architectures.
Cabral, Bruno +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Ordered multisignatures and identity-based sequential aggregate signatures, with applications to secure routing [PDF]
Proceedings of the 14th ACM conference on Computer and communications security, 2007 We construct new multiparty signature schemes that allow multiple signers to sequentially produce a compact, fixed-length signature simultaneously attesting to the message(s) they want to sign. First, we introduce a new primitive that we call ordered multisignatures (OMS), which allow signers to attest to a common message as well as the order in which ...
Alexandra Boldyreva +3 more
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
ISDSR: Secure DSR with ID-based Sequential Aggregate Signature
Proceedings of the 13th International Joint Conference on e-Business and Telecommunications, 2016 Wireless sensor networks are often more vulnerable than wired ones. Especially, an adversary can attack the networks by utilizing false route information. A countermeasure against the attack is a secure routing protocol with digital signatures to guarantee the validity of route information.
Toru Fujiwara +3 more
openaire +1 more source
An identity based routing path verification scheme for wireless sensor networks [PDF]
, 2018 While the ability to express routing policies in wireless sensor networks (WSNs) has been well-studied, unfortunately, the ability to enforce these policies has not been.
Khan, Haibat
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source