Results 41 to 50 of about 1,183,388 (183)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Security Analysis of Aggregate signature and Batch verification signature schemes [PDF]

, 2009
An identity based signature scheme allows any pair of users to communicate securely and to verify each others signatures without exchanging public key certificates. An aggregate signature scheme is a digital signature scheme which supports aggregation of
S. Sharmila Deva Selvi, S. Sree Vivek, J. Shriram, C. Pandu Rangan, S. Kalaivani   +4 more
core   +1 more source

Sequential Aggregate Signatures with Short Public Keys: Design, Analysis and Implementation Studies [PDF]

, 2012
The notion of aggregate signature has been motivated by applications and it enables any user to compress different signatures signed by different signers on different messages into a short signature.
Moti Yung, Dong Hoon Lee, Kwangsu Lee
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Certicateless Aggregate Short Signature Scheme [PDF]

, 2016
An aggregate signature scheme is the aggregation of multiple signatures into a single compact signature of short string that can convince to any arbitrary verifier participating in the scheme.
Jayaprakash Kar
core   +1 more source

Code-based Sequential Aggregate Signature Scheme

Computers, Materials & Continua, 2022
Bennian Dou, Lei Xu, Xiao-Ling Yu, Lin Mei, Cong Zuo   +4 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Unrestricted Aggregate Signatures [PDF]

, 2006
Secure use of the BGLS [7] aggregate signature schemes is restricted to the aggregation of distinct messages (for the basic scheme) or per-signer distinct messages (for the enhanced, prepend-public-key version of the scheme).
Mihir Bellare, Gregory Neven, Chanathip Namprempre   +2 more
core   +1 more source