Results 31 to 40 of about 18,713 (263)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
IEEE AccessPortfolio optimization is a primary component of the decision-making process in finance, aiming to tactfully allocate assets to achieve optimal returns while considering various constraints.
Chansreynich Huot +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012 Optimum segmented blank holder shape and its variable blank holder gaps (VBHGs) are determined by a sequential approximate optimization (SAO) with radial basis function network. In deep drawing, wrinkling and tearing of blank sheet are major defects. The
Jirasak SRIRAT +2 more
doaj +1 more source
Scientific Reports, 2020 The demand for high-capacity lithium-ion batteries (LIB) in electric vehicles has increased. In this study, optimization to maximize the specific energy density of a cell is conducted using the LIB electrochemical model and sequential approximate ...
Ji-San Kim +3 more
doaj +1 more source
Surrogate-Based Optimization Design for Air-Launched Vehicle Using Iterative Terminal Guidance
Aerospace, 2022 In recent years, the penetration of low-cost air-launched vehicles for nano/micro satellites has significantly increased worldwide. Conceptual design and overall parameters optimization of the air-launched vehicle has become an exigent task.
Jiaxin Li, Donghui Wang, Weihua Zhang
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2015 In hybrid electric vehicles (HEVs), an internal combustion engine (ICE) and electric motors (EMs) are equipped for improving the fuel consumption as well as the exhaust emissions. To improve them simultaneously, a well-organized energy management system (
Marina SAIKYO +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source