Results 31 to 40 of about 17,798 (304)

Multi-objective optimization for minimizing weldline and cycle time in rapid heating cycle molding using variable packing pressure profile

open access: yesNihon Kikai Gakkai ronbunshu, 2022
In plastic injection molding (PIM), weldline affects the strength and surface quality of products, and it is then important to determine the optimal process parameters for the weldline reduction. Rapid heat cycle molding (RHCM) that actively controls the
Shogo TSURITA   +5 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Enhancing Knapsack-Based Financial Portfolio Optimization Using Quantum Approximate Optimization Algorithm

open access: yesIEEE Access
Portfolio optimization is a primary component of the decision-making process in finance, aiming to tactfully allocate assets to achieve optimal returns while considering various constraints.
Chansreynich Huot   +3 more
doaj   +1 more source

Surrogate-Based Optimization Design for Air-Launched Vehicle Using Iterative Terminal Guidance

open access: yesAerospace, 2022
In recent years, the penetration of low-cost air-launched vehicles for nano/micro satellites has significantly increased worldwide. Conceptual design and overall parameters optimization of the air-launched vehicle has become an exigent task.
Jiaxin Li, Donghui Wang, Weihua Zhang
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Optimization of Segmented Blank Holder Shape and Its Variable Blank Holder Gap in Deep-Drawing Process

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
Optimum segmented blank holder shape and its variable blank holder gaps (VBHGs) are determined by a sequential approximate optimization (SAO) with radial basis function network. In deep drawing, wrinkling and tearing of blank sheet are major defects. The
Jirasak SRIRAT   +2 more
doaj   +1 more source

Optimization for maximum specific energy density of a lithium-ion battery using progressive quadratic response surface method and design of experiments

open access: yesScientific Reports, 2020
The demand for high-capacity lithium-ion batteries (LIB) in electric vehicles has increased. In this study, optimization to maximize the specific energy density of a cell is conducted using the LIB electrochemical model and sequential approximate ...
Ji-San Kim   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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