Results 131 to 140 of about 213,163 (336)
The impact of student psychological empowerment on class stickiness
IntroductionSustaining student engagement (“class stickiness”) in hybrid/online courses is essential for learning and retention. Grounded in customer-engagement theory, we test a sequential model where student psychological empowerment fosters ...
Hongping Fei +3 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Yong Chong,1 Shinji Shimoda,1 Noriko Miyake,1 Takatoshi Aoki,2 Yoshikiyo Ito,3 Tomohiko Kamimura,2 Nobuyuki Shimono4 1Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 2Department of Blood and Marrow ...
Chong Y +6 more
doaj
The digitization of college student management is a crucial approach for training institutions to decrease management costs while enhancing the quality of students’ development.
Wei Zou +3 more
doaj +1 more source
An evaluation of scaffolding for virtual interactive tutorials [PDF]
Scaffolding refers to a temporary support framework used during construction. Applied to teaching and learning it describes measures to support a learner to become confident and self-reliant in a subject. In a Web environment scaffolding features need to
Pahl, Claus
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Revisiting On-Line Discussion as Practice for Reflective Thinking in Three Sequential Classes
In a previous study, the authors questioned the potential of an on-line environment for increasing productive reflection in three sequential education classes.
Dittrich, Charles +3 more
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

