Results 171 to 180 of about 213,163 (336)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Sequential adaptive e-learning and hands-on simulator training for unilateral biportal endoscopy (UBE) of the lumbar spine - results from an EANS Young Neurosurgeons hands-on course [PDF]

Stefan Motov, Xavier A Santander, Felix C. Stengel, Malte Mohme, Michael Schwake, Cesare Zoia, V. M. Butenschoen, M. Bauer, Laura Lippa, David Belo, Stanislav Kaprovoy, Milan Lepić, Dominika Šťastná, Evangelos Drosos, Toma Spiriev, Margherita Giamundo, Fábio Torregrossa, Cornel Aldea, Giuseppe Maria Raffa, Carsten Ostendorp, Oliver Bozinov, Martin N. Stienen   +21 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Trauma Training for Emergency Department Physicians in Low- and Middle-Income Countries: A Scoping Review. [PDF]

AEM Educ Train
Nelson JB, Soistmann R, Reyes AM, Chang B, Kis M, Parker T, DeLong C, Eisner J, Valenzuela R, Carter NH, Kaufman JI, Pust GD, Ruiz G, Valenzuela JY.   +13 more
europepmc   +1 more source

Recognition of Facial Expression Based on Analysis of Resultant Sequential Retinal Outlines over The Course of A Blink

, 2011
Yasuhiro Ogoshi, Yoshinori Mitsuhashi, Sakiko Ogoshi, Akio Nakai, Shinya Matsuura, Chikahiro Araki   +5 more
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

A case report of enduring benefit of sequential PRRT in malignant insulinoma. [PDF]

EJNMMI Rep
Wang Zhang CA, Driessens N, Mileva M, Deleporte A, Flamen P, Karfis I.   +5 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Considerations for Estimating Causal Effects of Informatively Timed Treatments. [PDF]

Epidemiology
Oganisian A.
europepmc   +1 more source

232eP Preoperative short-course radiotherapy combined with tislelizumab followed by sequential immunotherapy combined with chemotherapy for locally advanced rectal cancer: A single-center phase II study

Peiyan Qin, X. Geng, T. Liu, Y. Li, N. Wang, Shuangshuang Zheng, Y. Guo, Xiaogang Leng, Hui-qi Ren, Q. Li, Y. Zhang, Jinghua Sun, Furong Hao   +12 more
openalex   +1 more source