Results 181 to 190 of about 212,365 (278)

Physical activity to reduce cardiometabolic risk in veterans and their families: protocol for an interdisciplinary investigation with toolkit co-design. [PDF]

Front Sports Act Living
Ferris LJ, Hawke P, Knight E, Burton NW, Keating SE.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Granulocyte and monocyte adsorption therapy in sepsis: a propensity score-matched analysis. [PDF]

J Intensive Care
Hisamune R, Yamakawa K, Nakamura T, Doi K, Takahashi G, Moriyama K, Ishihara T, Nishida O.   +7 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Combating Dermatologic Misinformation on Social Media via a Training Program for Health Care Professionals: Protocol for a 2-Phase Pilot Mixed Methods Study.

JMIR Res Protoc
Afolabi A, Brown E, Lyu JC, Ling PM, Rustad AM, Davis AE, Hoffman BL, Pugliano-Mauro M.   +7 more
europepmc   +1 more source

A case for qualitatively driven mixed methods in nursing research: a methodological discussion. [PDF]

J Res Nurs
Hamilton J, Cooper S, Ngune I, Cole A, Bostwick R, Massey DL.   +5 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Barriers and facilitators to implementing the living guideline development framework in oncology: a mixed methods study. [PDF]

BMJ Open
Ismaila N, Harvey BE, Einhaus K, Mbuagbaw L, Ma J, Thabane L.   +5 more
europepmc   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

The relationship between self-compassion and mental health: A repeated measures investigation. [PDF]

PLOS Ment Health
Wong MYC, Wong JY, Lam SKK, Fung HW.
europepmc   +1 more source