Results 71 to 80 of about 189,015 (264)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A Preliminary Study of the Effect of Bioavailable Fe and Co on the Anaerobic Digestion of Rice Straw

open access: yesEnergies, 2019
Rice straw is an abundant and sustainable substrate for anaerobic digestion (AD), but it is often deficient in essential trace elements (TEs) for proper microbial growth and metabolism.
Gabriele Mancini   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

DISTRIBUIÇÃO DE METAIS PESADOS NOS SEDIMENTOS DE FUNDO DOS RIOS CACERIBU E GUAXINDIBA, AFLUENTES DA BAÍA DE GUANABARA – RIO DE JANEIRO, BRASIL [PDF]

open access: yesGeochimica Brasiliensis, 2015
The Caceribu e Guaxindiba Rivers are two important tributaries of Guanabara Bay – RJ. Both are included in two protection environmental area and they are passive from sources and intense differences.
Liliane Jucá Lemos da Silva Porto   +5 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Evaluation of Fractions Obtained Through Steam Distillation and Hydroalcoholic Maceration of Wood Chips from Pinus mugo for Flavouring Italian Spirit grappa

open access: yesBeverages
In the Italian Alps, mountain pine (Pinus mugo) is traditionally used to flavour the Italian spirit grappa. While its shoots and needles are well-studied, little is known about the potential of its wood and bark.
Anna Perbellini   +4 more
doaj   +1 more source

Distribution and Potential Mobility of Selected Heavy Metals in a Fluvial Environment Under the Influence of Tanneries

open access: yesE3S Web of Conferences, 2013
In this study we evaluated the occurrence of heavy metals in a fluvial environment under the influence of tanneries – the Cadeia and Feitoria rivers basin (RS, south Brazil), highlighting the distribution and potential mobility of the selected elements ...
Rodrigues M. L. K., Formoso M. L. L.
doaj   +1 more source

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