Results 41 to 50 of about 15,344 (314)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Several Remarks on Banach–Mazur Games and its Applications Ewa Drabik

Foundations of Management, 2013
Certain type of perfect information games (PI-games), the so-called Banach-Mazur games, so far have not been applied in economy. The perfect information positional game is defined as the game during which at any time the choice is made by one of the ...
Drabik Ewa
doaj   +1 more source

Sequential Equilibrium in Computational Games [PDF]

ACM Transactions on Economics and Computation, 2019
We examine sequential equilibrium in the context ofcomputational games(Halpern and Pass 2015), where agents are charged for computation. In such games, an agent can rationally choose to forget, so issues of imperfect recall arise. In this setting, we consider two notions of sequential equilibrium.
Halpern, Joseph Y., Pass, Rafael
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

The Sequential Hotelling Game with One Parameterized Location

AppliedMath
This article studies the location–price Hotelling game. Numerous studies have been conducted on the Hotelling game with simultaneous decisions; however, in real-life scenarios, decisions are frequently sequential. Unfortunately, studies on the sequential
Luis Garcia-Perez, Juan Grau-Climent, Juan C. Losada, Ramon Alonso-Sanz   +3 more
doaj   +1 more source

Evolution of Decisions in Population Games with Sequentially Searching Individuals

Games, 2015
In many social situations, individuals endeavor to find the single best possible partner, but are constrained to evaluate the candidates in sequence.
Tadeas Priklopil, Krishnendu Chatterjee
doaj   +1 more source

Network of Games: An Ecology of Games Informing Integral and Inclusive City Developments

Urban Planning, 2022
This article analyzes possibilities for connecting individual city games for building a network of games working together. City gaming works along with the understanding that cities are self-organizing systems, influenced by multiple bottom-up and top ...
Ekim Tan
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

A sequential Attacker-Defender game for distribution systems resilience enhancement against extreme weather events

International Journal of Electrical Power & Energy Systems
Improving distribution system resilience against frequent extreme weather events is important for reliable power system operations. Especially when dealing with events such as hurricanes that have short-term predictions, proactive pre-event preparedness ...
Xiaofei Wang, Weijia Liu, Mengmeng Cai, Fei Ding, Junbo Zhao, Xinxuan Zhang   +5 more
doaj   +1 more source

DESEM: Depthwise Separable Convolution-Based Multimodal Deep Learning for In-Game Action Anticipation

IEEE Access, 2023
In real-time strategy (RTS) games, to defeat their opponents, players need to choose and implement the correct sequential actions. Because RTS games like StarCraft II are real-time, players have a very limited time to choose how to develop their strategy.
Changhyun Kim, Jinsoo Bae, Insung Baek, Jaeyoon Jeong, Young Jae Lee, Kiwoong Park, Sang Heun Shim, Seoung Bum Kim   +7 more
doaj   +1 more source