Results 41 to 50 of about 2,962,161 (302)

A Graph-Based Differentially Private Algorithm for Mining Frequent Sequential Patterns

Applied Sciences, 2022
Currently, individuals leave a digital trace of their activities when they use their smartphones, social media, mobile apps, credit card payments, Internet surfing profile, etc.
Miguel Nunez-del-Prado, Yoshitomi Maehara-Aliaga, Julián Salas, Hugo Alatrista-Salas, David Megías   +4 more
doaj   +1 more source

On efficiently mining high utility sequential patterns

, 2016
High utility sequential pattern mining is an emerging topic in pattern mining, which refers to identify sequences with high utilities (e.g., profits) but probably with low frequencies. To identify high utility sequential patterns, due to lack of downward
Wang, Jun-Zhe;Huang, Jiun-Long;Chen, Yi-Cheng
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

CloSpan Sequential Pattern Mining for Books Recommendation System in Petra Christian University Library [PDF]

, 2013
Petra Christian University (PCU) Library has been using website for their books search system. To further improve the service, it is necessary to develop the automatic system which can recommends the book or the correlation or the book which often ...
Yulia,, GUNAWAN, HERY PRASETYO, Satiabudhi, Gregorius   +2 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Spatiotemporal Mining of Time-Series Remote Sensing Images Based on Sequential Pattern Mining [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
With the continuous development of satellite techniques, it is now possible to acquire a regular series of images concerning a given geographical zone with both high accuracy and low cost.
H. C. Liu, G. J. He, X. M. Zhang, W. Jiang, S. G. Ling   +4 more
doaj   +1 more source

Performance Evaluation of Sequential Rule Mining Algorithms

Applied Sciences, 2022
Data mining techniques are useful in discovering hidden knowledge from large databases. One of its common techniques is sequential rule mining. A sequential rule (SR) helps in finding all sequential rules that achieved support and confidence threshold ...
Amira Abdelwahab, Nesma Youssef
doaj   +1 more source

Sequential Pattern Mining and Nonmonotonic Reasoning for Intelligent Information Agents

, 2007
With the explosive growth of information available on the Internet, more effective data mining and data reasoning mechanism is required to process the sheer volume of information. Belief revision logic offers the expressive power to represent information
Lau, Raymond, Lau, Raymond Y. K., Wu, Shengtang, Wu, Sheng-Tang, Li, Yuefeng, Zhou, Xujuan   +5 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source