Results 51 to 60 of about 14,528 (304)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Sequential Mining: Patterns and Algorithms Analysis
CoRR, 2013 This paper presents and analysis the common existing sequential pattern mining algorithms. It presents a classifying study of sequential pattern-mining algorithms into five extensive classes. First, on the basis of Apriori-based algorithm, second on Breadth First Search-based strategy, third on Depth First Search strategy, fourth on sequential closed ...
Thabet Slimani, Amor Lazzez
openaire +2 more sources
, 2016 Sequential pattern mining is to discover frequent sequential patterns in a sequence database. The technique is applied to fields such as web click-stream mining, failure forecast, and traf- fic analysis.
Shyur, Huan-Jyh;Jou, Chichang;Cheng, Chi-Bin;Yen, Chih-Yu +2 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
An Efficient Parallel Method for Mining Frequent Closed Sequential Patterns
IEEE Access, 2017 Mining frequent closed sequential pattern (FCSPs) has attracted a great deal of research attention, because it is an important task in sequences mining.
Bao Huynh, Bay Vo, Vaclav Snasel
doaj +1 more source
Repetitive nonoverlapping sequential pattern mining
CoRR, 2023 Sequential pattern mining (SPM) is an important branch of knowledge discovery that aims to mine frequent sub-sequences (patterns) in a sequential database. Various SPM methods have been investigated, and most of them are classical SPM methods, since these methods only consider whether or not a given pattern occurs within a sequence.
Meng Geng +6 more
openaire +2 more sources
Finding anomalies in SCADA logs using rare sequential pattern mining
, 2016 Pattern mining is a branch of data mining used to discover hidden patterns or correlations among data. We use rare sequential pattern mining to find anomalies in critical infrastructure control networks such as supervisory control and data acquisition ...
Radke, Kenneth +11 more
core +1 more source
Mining association rules for the quality improvement of the production process [PDF]
, 2013 Academics and practitioners have a common interest in the continuing development of methods and computer applications that support or perform knowledge-intensive engineering tasks.
Rigal, Fabien +2 more
core +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source